Detailed information NTG0310134

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: CH597_RS03870
• Genome accession: NZ_CP031688
• Coordinates: 750861..751553 (+)
• Length: 230 a.a.
• NCBI ID: WP_038440789.1
• Uniprot ID: A0AAJ8WR53
• Organism: Haemophilus influenzae strain P636-8296
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 745861..756553

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CH597_RS03850 (CH597_03845)	ampD	747132..747692 (-)	561	WP_070828280.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
CH597_RS03855 (CH597_03850)	pilA	747807..748256 (+)	450	WP_011271973.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
CH597_RS03860 (CH597_03855)	pilB	748253..749647 (+)	1395	WP_011271972.1	GspE/PulE family protein	Machinery gene
CH597_RS03865 (CH597_03860)	pilC	749644..750864 (+)	1221	WP_011271971.1	type II secretion system F family protein	Machinery gene
CH597_RS03870 (CH597_03865)	pilD	750861..751553 (+)	693	WP_038440789.1	prepilin peptidase	Machinery gene
CH597_RS03875 (CH597_03870)	rho	751607..752869 (-)	1263	WP_005629550.1	transcription termination factor Rho	-
CH597_RS03880 (CH597_03875)	metJ	753117..753434 (+)	318	WP_005631186.1	met regulon transcriptional regulator MetJ	-
CH597_RS03885 (CH597_03880)	cueR	753448..753834 (-)	387	WP_005663006.1	Cu(I)-responsive transcriptional regulator	-
CH597_RS03890 (CH597_03885)	-	753911..754117 (+)	207	WP_005631184.1	heavy-metal-associated domain-containing protein	-
CH597_RS03895 (CH597_03890)	-	754192..754398 (+)	207	WP_005686717.1	heavy-metal-associated domain-containing protein	-
CH597_RS03900 (CH597_03895)	-	754472..754678 (+)	207	WP_005686717.1	heavy-metal-associated domain-containing protein	-
CH597_RS03905 (CH597_03900)	-	754752..754958 (+)	207	WP_005631184.1	heavy-metal-associated domain-containing protein	-
CH597_RS03910 (CH597_03905)	-	755032..755238 (+)	207	WP_005686717.1	heavy-metal-associated domain-containing protein	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26786.77 Da
• Isoelectric Point: 8.6895

>NTDB_id=310134 CH597_RS03870 WP_038440789.1 750861..751553(+) (pilD) [Haemophilus influenzae strain P636-8296]
MIYFTMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNSSPFQPHFASIQQKKCGHILRYFFSIGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGTDNNFSLLTLSESIKSAAIFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHRKKKEFLPFAPFMNLSAVIIYFVKYYGY

Nucleotide

• Length: 693 bp

>NTDB_id=310134 CH597_RS03870 WP_038440789.1 750861..751553(+) (pilD) [Haemophilus influenzae strain P636-8296]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACAGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTTAGTATTGGGGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGCACAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTATTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAGAAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (92-199)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Haemophilus influenzae 86-028NP	97.391	100	0.974
pilD	Haemophilus influenzae Rd KW20	95.652	100	0.957