Detailed information    

insolico Bioinformatically predicted

Overview


Name   cipB   Type   Regulator
Locus tag   ES300_RS02500 Genome accession   NZ_CP038251
Coordinates   495081..495230 (+) Length   49 a.a.
NCBI ID   WP_001818346.1    Uniprot ID   Q9FBH1
Organism   Streptococcus pneumoniae strain TVO_1901944     
Function   indirect induction of ComX; activation of comRS system (predicted from homology)   
Competence regulation

Genomic Context


Location: 490081..500230
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES300_RS02455 (ES300_02585) blpI 490993..491190 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  ES300_RS02460 (ES300_02595) blpJ 491656..491925 (+) 270 WP_001093249.1 bacteriocin-like peptide BlpJ -
  ES300_RS02465 - 491994..492223 (+) 230 Protein_493 Blp family class II bacteriocin -
  ES300_RS02470 (ES300_02605) - 492226..492345 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  ES300_RS02475 (ES300_02610) - 492642..492806 (+) 165 WP_000727118.1 hypothetical protein -
  ES300_RS02480 (ES300_02615) - 492803..493207 (+) 405 WP_000846943.1 hypothetical protein -
  ES300_RS02485 (ES300_02620) - 493410..494214 (+) 805 WP_128903587.1 IS5 family transposase -
  ES300_RS02490 (ES300_02625) blpM 494364..494618 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  ES300_RS02495 (ES300_02630) blpN 494634..494837 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  ES300_RS02500 (ES300_02640) cipB 495081..495230 (+) 150 WP_001818346.1 bacteriocin-like peptide BlpO Regulator
  ES300_RS10850 - 495266..495331 (+) 66 Protein_501 ComC/BlpC family peptide pheromone/bacteriocin -
  ES300_RS02505 (ES300_02645) - 495334..495453 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  ES300_RS02510 (ES300_02655) - 496316..497662 (+) 1347 WP_001809444.1 IS1380-like element ISSpn5 family transposase -
  ES300_RS02515 (ES300_02660) - 497947..498330 (+) 384 WP_000877381.1 hypothetical protein -
  ES300_RS02520 (ES300_02665) - 498382..499071 (+) 690 WP_000760529.1 CPBP family intramembrane glutamic endopeptidase -
  ES300_RS02525 (ES300_02670) blpZ 499113..499346 (+) 234 WP_001849865.1 immunity protein BlpZ -
  ES300_RS02530 (ES300_02680) - 499497..500108 (+) 612 WP_000394037.1 CPBP family intramembrane glutamic endopeptidase -

Sequence


Protein


Download         Length: 49 a.a.        Molecular weight: 5134.91 Da        Isoelectric Point: 3.9133

>NTDB_id=310081 ES300_RS02500 WP_001818346.1 495081..495230(+) (cipB) [Streptococcus pneumoniae strain TVO_1901944]
MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDGCATTV

Nucleotide


Download         Length: 150 bp        

>NTDB_id=310081 ES300_RS02500 WP_001818346.1 495081..495230(+) (cipB) [Streptococcus pneumoniae strain TVO_1901944]
ATGGATACAAAAATGATGTCACAATTTGCAGTTATGGATAATGAAATGCTTGCTTGCGTTGAAGGTGGAGATATTGATTG
GGGAAGAAAAATTAGTTGTGCAGCAGGGGTTGCATATGGCGCAATTGATGGGTGTGCAACAACGGTTTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q9FBH1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cipB Streptococcus mutans UA159

51.02

100

0.51


Multiple sequence alignment