Detailed information NTG0309686

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: DD548_RS14435
• Genome accession: NZ_CP031673
• Coordinates: 2743220..2744107 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain MOZ66
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2738220..2749107

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DD548_RS14400 (DD548_14400)	-	2738239..2738331 (+)	93	WP_010956583.1	hypothetical protein	-
DD548_RS14405 (DD548_14405)	-	2738439..2738936 (-)	498	WP_001065268.1	glutathione peroxidase	-
DD548_RS14410 (DD548_14410)	-	2738946..2739206 (-)	261	WP_001789910.1	hypothetical protein	-
DD548_RS14420 (DD548_14420)	-	2739588..2739701 (-)	114	WP_011447078.1	hypothetical protein	-
DD548_RS14425 (DD548_14425)	-	2740360..2742360 (-)	2001	WP_000776751.1	ABC transporter permease	-
DD548_RS14430 (DD548_14430)	-	2742357..2743112 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
DD548_RS14435 (DD548_14435)	braS	2743220..2744107 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
DD548_RS14440 (DD548_14440)	braR	2744118..2744783 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
DD548_RS14445 (DD548_14445)	-	2744809..2745009 (-)	201	WP_000604728.1	hypothetical protein	-
DD548_RS14450 (DD548_14450)	-	2745207..2746631 (+)	1425	WP_000953744.1	alkaline phosphatase	-
DD548_RS15160 (DD548_14455)	-	2746691..2746792 (-)	102	WP_000731972.1	SE2200 family small protein	-
DD548_RS14460 (DD548_14460)	-	2746914..2747369 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DD548_RS14465 (DD548_14465)	-	2747614..2748375 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=309686 DD548_RS14435 WP_000143419.1 2743220..2744107(-) (braS) [Staphylococcus aureus strain MOZ66]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=309686 DD548_RS14435 WP_000143419.1 2743220..2744107(-) (braS) [Staphylococcus aureus strain MOZ66]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997