Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DD548_RS04165 Genome accession   NZ_CP031673
Coordinates   819455..820171 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain MOZ66     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 814455..825171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DD548_RS04145 (DD548_04145) - 815549..816499 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  DD548_RS04150 (DD548_04150) - 816648..818132 (+) 1485 WP_117224538.1 sucrose-6-phosphate hydrolase -
  DD548_RS04155 (DD548_04155) - 818129..819088 (+) 960 WP_001253312.1 carbohydrate kinase family protein -
  DD548_RS04160 (DD548_04160) - 819276..819383 (-) 108 WP_001790167.1 hypothetical protein -
  DD548_RS04165 (DD548_04165) agrA 819455..820171 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  DD548_RS04170 (DD548_04170) agrC 820190..821482 (-) 1293 WP_192875436.1 quorum-sensing sensor histidine kinase AgrC -
  DD548_RS04175 (DD548_04175) agrD 821507..821647 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  DD548_RS04180 (DD548_04180) agrB 821644..822213 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  DD548_RS15125 hld 822503..822583 (+) 81 WP_000046022.1 delta-hemolysin -
  DD548_RS04190 (DD548_04190) - 823180..823965 (-) 786 WP_117224539.1 carbon-nitrogen family hydrolase -
  DD548_RS04195 (DD548_04195) - 824326..824952 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=309653 DD548_RS04165 WP_000688492.1 819455..820171(-) (agrA) [Staphylococcus aureus strain MOZ66]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=309653 DD548_RS04165 WP_000688492.1 819455..820171(-) (agrA) [Staphylococcus aureus strain MOZ66]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment