Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | DZN22_RS01185 | Genome accession | NZ_CP031637 |
| Coordinates | 209392..210753 (+) | Length | 453 a.a. |
| NCBI ID | WP_002991192.1 | Uniprot ID | Q1JNL0 |
| Organism | Streptococcus pyogenes strain MGAS10786 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 173791..209311 | 209392..210753 | flank | 81 |
Gene organization within MGE regions
Location: 173791..210753
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DZN22_RS01020 (DZN22_01020) | - | 173791..174987 (+) | 1197 | WP_002986345.1 | glycine betaine/L-proline ABC transporter ATP-binding protein | - |
| DZN22_RS01025 (DZN22_01025) | - | 175003..176730 (+) | 1728 | WP_011284468.1 | ABC transporter permease/substrate binding protein | - |
| DZN22_RS01030 (DZN22_01030) | polA | 176861..179503 (+) | 2643 | WP_011284469.1 | DNA polymerase I | - |
| DZN22_RS01035 (DZN22_01035) | - | 179690..180145 (+) | 456 | WP_002987917.1 | CoA-binding protein | - |
| DZN22_RS01040 (DZN22_01040) | perR | 180197..180664 (+) | 468 | WP_002987920.1 | peroxide-responsive transcriptional repressor PerR | - |
| DZN22_RS01045 (DZN22_01045) | - | 180884..181120 (+) | 237 | WP_015055907.1 | hypothetical protein | - |
| DZN22_RS01050 (DZN22_01050) | - | 181342..182676 (+) | 1335 | WP_002987923.1 | phosphoadenosine phosphosulfate reductase | - |
| DZN22_RS01055 (DZN22_01055) | - | 182669..183199 (+) | 531 | WP_002987925.1 | ParB/RepB/Spo0J family partition protein | - |
| DZN22_RS09925 | - | 183246..183401 (-) | 156 | Protein_157 | ISL3 family transposase | - |
| DZN22_RS01065 (DZN22_01065) | - | 183528..184678 (-) | 1151 | Protein_158 | IS3 family transposase | - |
| DZN22_RS01070 (DZN22_01070) | - | 184756..186066 (-) | 1311 | WP_011284473.1 | SLC13 family permease | - |
| DZN22_RS01075 (DZN22_01075) | nadC | 186290..187162 (+) | 873 | WP_021340668.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| DZN22_RS01085 (DZN22_01085) | - | 188890..189753 (-) | 864 | WP_002986324.1 | DUF975 family protein | - |
| DZN22_RS10225 (DZN22_01090) | - | 189790..189975 (+) | 186 | WP_002986321.1 | hypothetical protein | - |
| DZN22_RS01095 (DZN22_01095) | tgt | 189972..191114 (+) | 1143 | WP_002986319.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| DZN22_RS01100 (DZN22_01100) | - | 191331..191642 (+) | 312 | WP_002987947.1 | CHY zinc finger protein | - |
| DZN22_RS01105 (DZN22_01105) | - | 191646..192182 (+) | 537 | WP_011284477.1 | biotin transporter BioY | - |
| DZN22_RS01110 (DZN22_01110) | - | 192325..193104 (+) | 780 | WP_002986311.1 | MBL fold metallo-hydrolase | - |
| DZN22_RS01115 (DZN22_01115) | tadA | 193104..193619 (+) | 516 | WP_002992549.1 | tRNA adenosine(34) deaminase TadA | - |
| DZN22_RS01120 (DZN22_01120) | - | 194233..195465 (-) | 1233 | WP_020833235.1 | transglutaminase domain-containing protein | - |
| DZN22_RS01130 (DZN22_01130) | speG | 195865..196569 (+) | 705 | WP_010921857.1 | streptococcal pyrogenic exotoxin SpeG | - |
| DZN22_RS01135 (DZN22_01135) | - | 197025..198374 (+) | 1350 | WP_011284480.1 | glucose-6-phosphate isomerase | - |
| DZN22_RS01140 (DZN22_01140) | - | 198723..200231 (-) | 1509 | WP_011284481.1 | helix-turn-helix domain-containing protein | - |
| DZN22_RS01145 (DZN22_01145) | - | 200919..201590 (+) | 672 | WP_011284482.1 | rhomboid family intramembrane serine protease | - |
| DZN22_RS01150 (DZN22_01150) | galU | 201689..202588 (-) | 900 | WP_002986125.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| DZN22_RS01155 (DZN22_01155) | - | 202621..203637 (-) | 1017 | WP_011284483.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| DZN22_RS01160 (DZN22_01160) | - | 203935..204384 (+) | 450 | WP_002986120.1 | MarR family transcriptional regulator | - |
| DZN22_RS01165 (DZN22_01165) | - | 204377..206083 (+) | 1707 | WP_011284484.1 | ABC transporter ATP-binding protein | - |
| DZN22_RS01170 (DZN22_01170) | - | 206086..207870 (+) | 1785 | WP_021340815.1 | ABC transporter ATP-binding protein | - |
| DZN22_RS01175 (DZN22_01175) | - | 207988..208755 (+) | 768 | WP_011054158.1 | epoxyqueuosine reductase QueH | - |
| DZN22_RS01180 (DZN22_01180) | - | 208865..209311 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| DZN22_RS01185 (DZN22_01185) | radA | 209392..210753 (+) | 1362 | WP_002991192.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49358.62 Da Isoelectric Point: 6.0962
>NTDB_id=309038 DZN22_RS01185 WP_002991192.1 209392..210753(+) (radA) [Streptococcus pyogenes strain MGAS10786]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=309038 DZN22_RS01185 WP_002991192.1 209392..210753(+) (radA) [Streptococcus pyogenes strain MGAS10786]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCTACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGCGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGTTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTTGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCTACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGCGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGTTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTTGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae D39 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae R6 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae Rx1 |
85.43 |
100 |
0.854 |
| radA | Streptococcus mitis SK321 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae TIGR4 |
85.43 |
100 |
0.854 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |