Detailed information NTG0308627

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZR90_RS02525
• Genome accession: NZ_CP031629
• Coordinates: 459019..460020 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS28278
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 454019..465020

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZR90_RS02500 (DZR90_02495)	-	454693..455376 (-)	684	WP_011017476.1	DUF969 domain-containing protein	-
DZR90_RS02505 (DZR90_02500)	-	455587..456513 (-)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZR90_RS02510 (DZR90_02505)	-	456658..457035 (-)	378	WP_002985686.1	VOC family protein	-
DZR90_RS02515 (DZR90_02510)	-	457046..457711 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZR90_RS02520 (DZR90_02515)	-	457760..458845 (-)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZR90_RS02525 (DZR90_02520)	ccpA	459019..460020 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZR90_RS02530 (DZR90_02525)	-	460151..461149 (+)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZR90_RS02535 (DZR90_02530)	-	461151..462485 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZR90_RS02540 (DZR90_02535)	thrS	462907..464850 (+)	1944	WP_011284591.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308627 DZR90_RS02525 WP_002985680.1 459019..460020(+) (ccpA) [Streptococcus pyogenes strain MGAS28278]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308627 DZR90_RS02525 WP_002985680.1 459019..460020(+) (ccpA) [Streptococcus pyogenes strain MGAS28278]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559