Detailed information NTG0308539

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZS66_RS07105
• Genome accession: NZ_CP031627
• Coordinates: 1414828..1415829 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS28360
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1409828..1420829

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZS66_RS07090 (DZS66_07085)	thrS	1409998..1411941 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZS66_RS07095 (DZS66_07090)	-	1412363..1413697 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZS66_RS07100 (DZS66_07095)	-	1413699..1414697 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZS66_RS07105 (DZS66_07100)	ccpA	1414828..1415829 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZS66_RS07110 (DZS66_07105)	-	1416003..1417088 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZS66_RS07115 (DZS66_07110)	-	1417137..1417802 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZS66_RS07120 (DZS66_07115)	-	1417813..1418190 (+)	378	WP_002985686.1	VOC family protein	-
DZS66_RS07125 (DZS66_07120)	-	1418335..1419261 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZS66_RS07130 (DZS66_07125)	-	1419472..1420155 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308539 DZS66_RS07105 WP_002985680.1 1414828..1415829(-) (ccpA) [Streptococcus pyogenes strain MGAS28360]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308539 DZS66_RS07105 WP_002985680.1 1414828..1415829(-) (ccpA) [Streptococcus pyogenes strain MGAS28360]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559