Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | DZS91_RS01180 | Genome accession | NZ_CP031626 |
| Coordinates | 208744..210105 (+) | Length | 453 a.a. |
| NCBI ID | WP_002991192.1 | Uniprot ID | Q1JNL0 |
| Organism | Streptococcus pyogenes strain MGAS28386 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 173143..208663 | 208744..210105 | flank | 81 |
Gene organization within MGE regions
Location: 173143..210105
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DZS91_RS01015 (DZS91_01015) | - | 173143..174339 (+) | 1197 | WP_002986345.1 | glycine betaine/L-proline ABC transporter ATP-binding protein | - |
| DZS91_RS01020 (DZS91_01020) | - | 174355..176082 (+) | 1728 | WP_011284468.1 | ABC transporter permease/substrate binding protein | - |
| DZS91_RS01025 (DZS91_01025) | polA | 176213..178855 (+) | 2643 | WP_011284469.1 | DNA polymerase I | - |
| DZS91_RS01030 (DZS91_01030) | - | 179042..179497 (+) | 456 | WP_002987917.1 | CoA-binding protein | - |
| DZS91_RS01035 (DZS91_01035) | perR | 179549..180016 (+) | 468 | WP_002987920.1 | peroxide-responsive transcriptional repressor PerR | - |
| DZS91_RS01040 (DZS91_01040) | - | 180236..180472 (+) | 237 | WP_015055907.1 | hypothetical protein | - |
| DZS91_RS01045 (DZS91_01045) | - | 180694..182028 (+) | 1335 | WP_002987923.1 | phosphoadenosine phosphosulfate reductase | - |
| DZS91_RS01050 (DZS91_01050) | - | 182021..182551 (+) | 531 | WP_002987925.1 | ParB/RepB/Spo0J family partition protein | - |
| DZS91_RS09245 | - | 182598..182753 (-) | 156 | Protein_156 | ISL3 family transposase | - |
| DZS91_RS01060 (DZS91_01060) | - | 182880..184030 (-) | 1151 | Protein_157 | IS3 family transposase | - |
| DZS91_RS01065 (DZS91_01065) | - | 184108..185418 (-) | 1311 | WP_011284473.1 | SLC13 family permease | - |
| DZS91_RS01070 (DZS91_01070) | nadC | 185642..186514 (+) | 873 | WP_021340668.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| DZS91_RS01080 (DZS91_01080) | - | 188242..189105 (-) | 864 | WP_002986324.1 | DUF975 family protein | - |
| DZS91_RS09525 (DZS91_01085) | - | 189142..189327 (+) | 186 | WP_002986321.1 | hypothetical protein | - |
| DZS91_RS01090 (DZS91_01090) | tgt | 189324..190466 (+) | 1143 | WP_002986319.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| DZS91_RS01095 (DZS91_01095) | - | 190683..190994 (+) | 312 | WP_002987947.1 | CHY zinc finger protein | - |
| DZS91_RS01100 (DZS91_01100) | - | 190998..191534 (+) | 537 | WP_011284477.1 | biotin transporter BioY | - |
| DZS91_RS01105 (DZS91_01105) | - | 191677..192456 (+) | 780 | WP_002986311.1 | MBL fold metallo-hydrolase | - |
| DZS91_RS01110 (DZS91_01110) | tadA | 192456..192971 (+) | 516 | WP_002992549.1 | tRNA adenosine(34) deaminase TadA | - |
| DZS91_RS01115 (DZS91_01115) | - | 193585..194817 (-) | 1233 | WP_020833235.1 | transglutaminase domain-containing protein | - |
| DZS91_RS01125 (DZS91_01125) | speG | 195217..195921 (+) | 705 | WP_010921857.1 | streptococcal pyrogenic exotoxin SpeG | - |
| DZS91_RS01130 (DZS91_01130) | - | 196377..197726 (+) | 1350 | WP_011284480.1 | glucose-6-phosphate isomerase | - |
| DZS91_RS01135 (DZS91_01135) | - | 198075..199583 (-) | 1509 | WP_021341130.1 | helix-turn-helix domain-containing protein | - |
| DZS91_RS01140 (DZS91_01140) | - | 200271..200942 (+) | 672 | WP_011284482.1 | rhomboid family intramembrane serine protease | - |
| DZS91_RS01145 (DZS91_01145) | galU | 201041..201940 (-) | 900 | WP_002986125.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| DZS91_RS01150 (DZS91_01150) | - | 201973..202989 (-) | 1017 | WP_011284483.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| DZS91_RS01155 (DZS91_01155) | - | 203287..203736 (+) | 450 | WP_002986120.1 | MarR family transcriptional regulator | - |
| DZS91_RS01160 (DZS91_01160) | - | 203729..205435 (+) | 1707 | WP_011284484.1 | ABC transporter ATP-binding protein | - |
| DZS91_RS01165 (DZS91_01165) | - | 205438..207222 (+) | 1785 | WP_021340815.1 | ABC transporter ATP-binding protein | - |
| DZS91_RS01170 (DZS91_01170) | - | 207340..208107 (+) | 768 | WP_011054158.1 | epoxyqueuosine reductase QueH | - |
| DZS91_RS01175 (DZS91_01175) | - | 208217..208663 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| DZS91_RS01180 (DZS91_01180) | radA | 208744..210105 (+) | 1362 | WP_002991192.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49358.62 Da Isoelectric Point: 6.0962
>NTDB_id=308456 DZS91_RS01180 WP_002991192.1 208744..210105(+) (radA) [Streptococcus pyogenes strain MGAS28386]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=308456 DZS91_RS01180 WP_002991192.1 208744..210105(+) (radA) [Streptococcus pyogenes strain MGAS28386]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCTACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGCGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGTTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTTGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCTACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGCGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGTTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTTGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae D39 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae R6 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae Rx1 |
85.43 |
100 |
0.854 |
| radA | Streptococcus mitis SK321 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae TIGR4 |
85.43 |
100 |
0.854 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |