Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   EZV63_RS19860 Genome accession   NZ_CP036534
Coordinates   4446040..4447164 (-) Length   374 a.a.
NCBI ID   WP_031047520.1    Uniprot ID   A0ABS7W1G9
Organism   Streptomyces sp. VN1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4441040..4452164
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EZV63_RS19840 (EZV63_20105) - 4441897..4443504 (+) 1608 WP_228773770.1 sensor histidine kinase -
  EZV63_RS19845 (EZV63_20110) - 4443501..4444181 (+) 681 WP_166624599.1 response regulator transcription factor -
  EZV63_RS19850 (EZV63_20115) - 4444286..4444936 (-) 651 WP_194963031.1 phosphatase PAP2 family protein -
  EZV63_RS19855 - 4445122..4445988 (+) 867 WP_166624601.1 hypothetical protein -
  EZV63_RS19860 (EZV63_20130) disA 4446040..4447164 (-) 1125 WP_031047520.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  EZV63_RS19865 (EZV63_20135) radA/sms 4447246..4448655 (-) 1410 WP_166624602.1 DNA repair protein RadA Machinery gene
  EZV63_RS19870 (EZV63_20140) - 4448965..4450776 (+) 1812 WP_228773771.1 hypothetical protein -
  EZV63_RS19875 (EZV63_20145) - 4450873..4451715 (-) 843 WP_031047530.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40061.80 Da        Isoelectric Point: 5.0058

>NTDB_id=308360 EZV63_RS19860 WP_031047520.1 4446040..4447164(-) (disA) [Streptomyces sp. VN1]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLRGNTGGLIVLGSDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQMLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=308360 EZV63_RS19860 WP_031047520.1 4446040..4447164(-) (disA) [Streptomyces sp. VN1]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCGCCCGGCACCTCCCTGCGCGACGGCCTGGAGCGGGTCCTGCGCGGCAACACCGGCGGTCTGATCGTGC
TGGGTTCCGACAAGACCGTCGAGTCGATGTGCACGGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTCTCCTCGGACCTGTCGAAGATCCTGCGGGCGGGCGTGCAGATGCTCCC
GGACCCCACGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACGGCGGACCGGGTCAGCAAACAGGTCGGCTTCCCCG
TCGTGTCCGTCTCGCAGTCCATGCGGCTGATCGCGCTGTACGTCGACGGGCAGCGGCGCGTGCTGGAGGACTCGGCGGCG
ATCCTGTCCCGGGCCAACCAGGCGCTGGCCACCCTGGAGCGGTACAAGCTGCGGCTCGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACCGTCCGGGACGTCTCGGCGGTCGCGCAGCGCCTGGAGATGGTGCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGGCGGCTGCTCGCGCTGCAGTTGGACGAGCTGATCGCC
GGTGTGGAGCCGGAGCGCGAGCTGGTCGTGCGGGACTACGTGCCCGAACCGACCGCGAAGCGGTCCCGCACGGTCGACGA
GGCACTGGCCGAGCTGGACAAGCTCAGCCACGCCGAGCTGCTCGAACTGTCCACGGTGGCCCGTGCCCTGGGCTACACCG
GGTCGCCCGAGACGCTGGACTCCGCCGTGTCGCCGCGCGGGTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGCCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTCGCCGCGAGCGTGGACGACCTGCAGACGGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGCAGCGTGCGCGAGGGCCTGTCGCGGCTGGCCGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.983

96.524

0.444

Multiple sequence alignment