Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EZV63_RS02035 Genome accession   NZ_CP036534
Coordinates   518016..518642 (+) Length   208 a.a.
NCBI ID   WP_031032761.1    Uniprot ID   -
Organism   Streptomyces sp. VN1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 513016..523642
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EZV63_RS02010 (EZV63_02065) nsrR 513827..514273 (-) 447 WP_031032749.1 nitric oxide-sensing transcriptional repressor NsrR -
  EZV63_RS02015 (EZV63_02070) - 514373..514813 (+) 441 WP_037770220.1 hypothetical protein -
  EZV63_RS02020 (EZV63_02075) - 514822..515505 (-) 684 WP_166623510.1 ABC transporter ATP-binding protein -
  EZV63_RS02025 (EZV63_02080) - 515502..516584 (-) 1083 WP_166623511.1 FtsX-like permease family protein -
  EZV63_RS02030 (EZV63_02085) - 516793..518001 (+) 1209 WP_166623512.1 sensor histidine kinase -
  EZV63_RS02035 (EZV63_02090) vraR 518016..518642 (+) 627 WP_031032761.1 response regulator transcription factor Regulator
  EZV63_RS02040 (EZV63_02095) - 518646..520409 (-) 1764 WP_166623513.1 MFS transporter -
  EZV63_RS02045 (EZV63_02100) - 520406..520891 (-) 486 WP_037770207.1 MarR family transcriptional regulator -
  EZV63_RS02050 (EZV63_02105) - 520994..521683 (+) 690 WP_037770205.1 GAF and ANTAR domain-containing protein -
  EZV63_RS02055 (EZV63_02110) - 521793..522194 (+) 402 WP_031032771.1 hypothetical protein -
  EZV63_RS36785 (EZV63_02115) - 522268..522375 (-) 108 Protein_378 mandelate racemase -
  EZV63_RS02065 (EZV63_02120) - 522507..523310 (+) 804 WP_031032775.1 hypothetical protein -

Sequence

Protein


Download         Length: 208 a.a.        Molecular weight: 21912.05 Da        Isoelectric Point: 6.0228

>NTDB_id=308317 EZV63_RS02035 WP_031032761.1 518016..518642(+) (vraR) [Streptomyces sp. VN1]
MPIRLLLADDHPVVRAGLRAVLETEEGITVAAEAATAEEAVERAGLGDIDVVLMDLRFGRGMNGARATAAITARPGAPRV
LIVTTYDTDADTLPAIEAGATGYLLKDAPPEELAAAVRTAAAGRTALAPTVADRLMTRLREPHTSLTRRETEVLSLVAEG
LSNQHVGERLHLTEGTVKSHLARVYAKLDVDSRTAAVAAATALGLIRR

Nucleotide


Download         Length: 627 bp        

>NTDB_id=308317 EZV63_RS02035 WP_031032761.1 518016..518642(+) (vraR) [Streptomyces sp. VN1]
ATGCCGATCCGGCTGCTGCTCGCCGACGACCACCCCGTGGTCCGCGCCGGGCTGCGCGCGGTGCTGGAGACCGAGGAGGG
CATCACCGTGGCCGCCGAGGCCGCGACCGCCGAGGAGGCCGTCGAGCGGGCGGGGCTCGGCGACATCGACGTCGTCCTGA
TGGACCTGAGGTTCGGCAGGGGCATGAACGGCGCCCGGGCCACCGCCGCGATCACCGCGCGGCCCGGGGCACCGCGCGTG
CTGATCGTCACCACGTACGACACCGACGCCGACACGCTGCCGGCCATTGAGGCCGGTGCCACGGGCTACCTCCTCAAGGA
CGCCCCGCCGGAGGAGCTCGCAGCGGCGGTGCGCACCGCCGCGGCGGGCCGGACCGCCCTCGCGCCGACGGTCGCGGACC
GCCTGATGACCCGCCTGCGCGAGCCGCACACCTCGCTGACCCGCCGCGAGACGGAGGTGCTCTCCCTGGTCGCCGAGGGC
CTGTCCAACCAGCACGTCGGTGAGCGGCTGCACCTGACCGAGGGCACGGTCAAGTCCCACCTGGCCCGGGTCTACGCCAA
GCTGGACGTGGACTCCCGCACCGCCGCGGTCGCCGCCGCCACCGCCCTCGGTCTCATCCGGCGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-117)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

35.714

100

0.361

Multiple sequence alignment