Detailed information NTG0308170

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EZY40_RS03640
• Genome accession: NZ_CP036530
• Coordinates: 707476..709575 (-)
• Length: 699 a.a.
• NCBI ID: WP_031488351.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain STAB09023
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 702476..714575

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EZY40_RS03610 (EZY40_03660)	-	702953..703792 (+)	840	WP_011017679.1	thymidylate synthase	-
EZY40_RS03615 (EZY40_03665)	-	703872..704369 (+)	498	WP_031488353.1	dihydrofolate reductase	-
EZY40_RS03625 (EZY40_03675)	clpX	704689..705918 (+)	1230	WP_031488352.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
EZY40_RS03630 (EZY40_03680)	yihA	705928..706527 (+)	600	WP_002990160.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
EZY40_RS03635 (EZY40_03685)	-	706675..707418 (+)	744	WP_002984942.1	hypothetical protein	-
EZY40_RS03640 (EZY40_03690)	clpC	707476..709575 (-)	2100	WP_031488351.1	AAA family ATPase	Regulator
EZY40_RS03645 (EZY40_03695)	rpiA	709953..710636 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-
EZY40_RS03650 (EZY40_03700)	-	710713..711924 (+)	1212	WP_031488350.1	phosphopentomutase	-
EZY40_RS03655 (EZY40_03705)	arsC	711943..712383 (+)	441	WP_023079098.1	arsenate reductase (glutaredoxin)	-
EZY40_RS03660 (EZY40_03710)	-	712367..713176 (+)	810	WP_031488349.1	purine-nucleoside phosphorylase	-
EZY40_RS03665 (EZY40_03715)	deoD	713839..714552 (+)	714	WP_002990147.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77244.34 Da
• Isoelectric Point: 5.7799

>NTDB_id=308170 EZY40_RS03640 WP_031488351.1 707476..709575(-) (clpC) [Streptococcus pyogenes strain STAB09023]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSGSNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIKQKDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=308170 EZY40_RS03640 WP_031488351.1 707476..709575(-) (clpC) [Streptococcus pyogenes strain STAB09023]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTTGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCCGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTTGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGGGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGAAGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TTAAGCAAAAAGATCAGTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

• AAA lid domain (AAA_lid_9) (259-353)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.084	100	0.474
clpE	Streptococcus mutans UA159	49.688	91.559	0.455
clpE	Streptococcus pneumoniae TIGR4	49.209	90.415	0.445
clpE	Streptococcus pneumoniae Rx1	49.209	90.415	0.445
clpE	Streptococcus pneumoniae D39	49.209	90.415	0.445
clpE	Streptococcus pneumoniae R6	49.209	90.415	0.445
clpC	Bacillus subtilis subsp. subtilis str. 168	44.812	95.136	0.426
clpC	Streptococcus thermophilus LMD-9	42.79	91.273	0.391
clpC	Streptococcus pneumoniae Rx1	41.871	93.276	0.391
clpC	Streptococcus pneumoniae D39	41.871	93.276	0.391
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.348	93.419	0.386
clpC	Streptococcus thermophilus LMG 18311	42.587	90.701	0.386
clpC	Streptococcus pneumoniae TIGR4	42.857	90.129	0.386
clpC	Streptococcus mutans UA159	41.562	91.559	0.381