Detailed information NTG0308115

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZ066_RS07715
• Genome accession: NZ_CP031619
• Coordinates: 1499807..1500808 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS29284
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1494807..1505808

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZ066_RS07700 (DZ066_07690)	thrS	1494977..1496920 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZ066_RS07705 (DZ066_07695)	-	1497342..1498676 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZ066_RS07710 (DZ066_07700)	-	1498678..1499676 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZ066_RS07715 (DZ066_07705)	ccpA	1499807..1500808 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZ066_RS07720 (DZ066_07710)	-	1500982..1502067 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZ066_RS07725 (DZ066_07715)	-	1502116..1502781 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZ066_RS07730 (DZ066_07720)	-	1502792..1503169 (+)	378	WP_002985686.1	VOC family protein	-
DZ066_RS07735 (DZ066_07725)	-	1503314..1504240 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZ066_RS07740 (DZ066_07730)	-	1504451..1505134 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308115 DZ066_RS07715 WP_002985680.1 1499807..1500808(-) (ccpA) [Streptococcus pyogenes strain MGAS29284]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308115 DZ066_RS07715 WP_002985680.1 1499807..1500808(-) (ccpA) [Streptococcus pyogenes strain MGAS29284]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559