Detailed information NTG0307646

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DNI88_RS03150
• Genome accession: NZ_CP031561
• Coordinates: 678987..680006 (+)
• Length: 339 a.a.
• NCBI ID: WP_189722240.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain AP20
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 673987..685006

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DNI88_RS03125 (DNI88_03135)	-	674243..674965 (+)	723	WP_014613476.1	type 1 glutamine amidotransferase	-
DNI88_RS03130 (DNI88_03140)	-	675933..676931 (-)	999	WP_037542644.1	aromatic acid exporter family protein	-
DNI88_RS03135 (DNI88_03145)	map	677028..677789 (+)	762	WP_014613478.1	type I methionyl aminopeptidase	-
DNI88_RS03140 (DNI88_03150)	-	677887..678276 (+)	390	WP_014613479.1	hypothetical protein	-
DNI88_RS03145 (DNI88_03155)	liaF	678289..678990 (+)	702	WP_014613480.1	cell wall-active antibiotics response protein LiaF	-
DNI88_RS03150 (DNI88_03160)	vraS	678987..680006 (+)	1020	WP_189722240.1	sensor histidine kinase	Regulator
DNI88_RS03155 (DNI88_03165)	vraR	679996..680625 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
DNI88_RS03160 (DNI88_03170)	-	681192..681773 (-)	582	WP_015729388.1	carbonic anhydrase	-
DNI88_RS03165 (DNI88_03175)	-	681806..683143 (-)	1338	WP_015729387.1	YihY/virulence factor BrkB family protein	-
DNI88_RS03170 (DNI88_03180)	-	683359..683646 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
DNI88_RS03175 (DNI88_03185)	-	683654..684112 (-)	459	WP_014613486.1	low molecular weight protein-tyrosine-phosphatase	-
DNI88_RS03180 (DNI88_03190)	-	684246..684449 (+)	204	WP_014613487.1	DUF1128 family protein	-

Sequence

Protein

• Length: 339 a.a.
• Molecular weight: 39038.02 Da
• Isoelectric Point: 5.0435

>NTDB_id=307646 DNI88_RS03150 WP_189722240.1 678987..680006(+) (vraS) [Staphylococcus pseudintermedius strain AP20]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVGSVLAYKINQQNDWLKQQIVRAFEG
ETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVSQQLFAASM
MLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEIDEFEVPKG
IEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGATFHIVSLPD
AGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1020 bp

>NTDB_id=307646 DNI88_RS03150 WP_189722240.1 678987..680006(+) (vraS) [Staphylococcus pseudintermedius strain AP20]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAACAAATCGTTCGTGCCTTTGAAGGT
GAAACAGTGGGCATCAATGATCAACAACTCGAGCTGTATAATGAAACGATTGAATTATATCAAGCACTCGTCCCATTAAA
TCAAGAATTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATAATTTAAATGATTTGAAGGTGAAAA
AGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCGCAACAACTTTTCGCGGCAAGTATG
ATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCCAACGTTAGAAAAAATGGTGCAAGA
CTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGGACAAATCGTTAGGTGAGGGAATTA
AATCGCTAGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATTGATGAGTTTGAAGTACCTAAAGGC
ATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACATGCTGAGGGGACGCAAGTAACGGT
AGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTGGATTTAATGTCGATGAAAAGTTAG
AACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACATTTCATATCGTCTCATTACCTGAT
GCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (241-333)

• Histidine kinase (HisKA_3) (139-202)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	82.421	100	0.844