Detailed information NTG0307419

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DV947_RS05375
• Genome accession: NZ_CP031545
• Coordinates: 1003606..1004487 (-)
• Length: 293 a.a.
• NCBI ID: WP_116920256.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST109
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 998606..1009487

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV947_RS05350 (DV947_05355)	vicR	999311..1000018 (-)	708	WP_011681206.1	response regulator YycF	Regulator
DV947_RS05355 (DV947_05360)	-	1000545..1001312 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
DV947_RS05360 (DV947_05365)	-	1001324..1002157 (+)	834	WP_116920255.1	transporter substrate-binding domain-containing protein	-
DV947_RS05365 (DV947_05370)	-	1002175..1002873 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
DV947_RS05370 (DV947_05375)	-	1002885..1003535 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
DV947_RS05375 (DV947_05380)	endA	1003606..1004487 (-)	882	WP_116920256.1	DNA/RNA non-specific endonuclease	Machinery gene
DV947_RS05380 (DV947_05385)	-	1004549..1004737 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
DV947_RS05385 (DV947_05390)	murA	1004739..1006010 (-)	1272	WP_116920257.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DV947_RS05390 (DV947_05395)	-	1006080..1006316 (-)	237	WP_002946959.1	DUF1146 family protein	-
DV947_RS05395 (DV947_05400)	galE	1006504..1007517 (-)	1014	WP_116920258.1	UDP-glucose 4-epimerase GalE	-
DV947_RS05400 (DV947_05405)	-	1007532..1007987 (-)	456	WP_240320552.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31817.55 Da
• Isoelectric Point: 10.1789

>NTDB_id=307419 DV947_RS05375 WP_116920256.1 1003606..1004487(-) (endA) [Streptococcus thermophilus strain ST109]
MVKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLSETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=307419 DV947_RS05375 WP_116920256.1 1003606..1004487(-) (endA) [Streptococcus thermophilus strain ST109]
ATGGTAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTAATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTTCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGACGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTAATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	70.238	86.007	0.604
endA	Streptococcus pneumoniae D39	70.238	86.007	0.604
endA	Streptococcus pneumoniae R6	70.238	86.007	0.604
endA	Streptococcus pneumoniae TIGR4	70.238	86.007	0.604