Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   DV947_RS01675 Genome accession   NZ_CP031545
Coordinates   306291..307808 (+) Length   505 a.a.
NCBI ID   WP_116920104.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST109     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 301291..312808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV947_RS10035 (DV947_01645) - 301571..301741 (+) 171 Protein_272 ascorbate 6-phosphate lactonase -
  DV947_RS01650 (DV947_01650) - 301758..302429 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  DV947_RS01655 (DV947_01655) - 302469..303833 (-) 1365 WP_116920103.1 potassium transporter TrkG -
  DV947_RS01660 (DV947_01660) rsmG 303903..304616 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DV947_RS01665 (DV947_01665) - 304913..305449 (+) 537 WP_014607968.1 YceD family protein -
  DV947_RS01670 (DV947_01670) covR 305605..306294 (+) 690 WP_014607969.1 response regulator transcription factor Regulator
  DV947_RS01675 (DV947_01675) covS 306291..307808 (+) 1518 WP_116920104.1 HAMP domain-containing histidine kinase Regulator
  DV947_RS01680 (DV947_01680) nrdR 307930..308409 (+) 480 WP_011680738.1 transcriptional regulator NrdR -
  DV947_RS01685 (DV947_01685) - 308406..309581 (+) 1176 WP_011680739.1 DnaD domain protein -
  DV947_RS01690 (DV947_01690) dnaI 309585..310487 (+) 903 WP_014607971.1 primosomal protein DnaI -
  DV947_RS01695 (DV947_01695) der 310593..311903 (+) 1311 WP_014607972.1 ribosome biogenesis GTPase Der -
  DV947_RS10505 - 311967..312626 (+) 660 Protein_283 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57534.91 Da        Isoelectric Point: 5.2689

>NTDB_id=307402 DV947_RS01675 WP_116920104.1 306291..307808(+) (covS) [Streptococcus thermophilus strain ST109]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSIYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSIPRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=307402 DV947_RS01675 WP_116920104.1 306291..307808(+) (covS) [Streptococcus thermophilus strain ST109]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTATCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCCTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

ArlS sensor domain (ArlS_N)

(39-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.223

99.406

0.937

Multiple sequence alignment