Detailed information NTG0307382

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: L3107_RS11625
• Genome accession: NZ_CP031538
• Coordinates: 2250298..2251329 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain 3107
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2245298..2256329

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L3107_RS11595 (L3107_2263)	-	2246501..2246998 (-)	498	WP_011677211.1	nitroreductase family protein	-
L3107_RS11600 (L3107_2264)	-	2246985..2247194 (-)	210	WP_011677212.1	hypothetical protein	-
L3107_RS11605 (L3107_2265)	-	2247191..2247415 (-)	225	WP_014573364.1	hypothetical protein	-
L3107_RS11610 (L3107_2266)	-	2247482..2248372 (+)	891	WP_081146373.1	IS982 family transposase	-
L3107_RS11615 (L3107_2267)	kwcM	2248479..2249798 (-)	1320	WP_014573366.1	KxxxW cyclic peptide radical SAM maturase	-
L3107_RS11620 (L3107_2268)	-	2249866..2249979 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
L3107_RS11625 (L3107_2269)	sepM	2250298..2251329 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
L3107_RS11630 (L3107_2270)	coaD	2251313..2251813 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
L3107_RS11635 (L3107_2271)	rsmD	2251861..2252400 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
L3107_RS11640 (L3107_2272)	-	2252571..2253791 (-)	1221	WP_021164847.1	MFS transporter	-
L3107_RS11645 (L3107_2273)	lmrP	2253875..2255101 (-)	1227	Protein_2272	multidrug efflux MFS transporter LmrP	-
L3107_RS11650 (L3107_2274)	-	2255289..2255783 (+)	495	WP_021164846.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=307382 L3107_RS11625 WP_011677213.1 2250298..2251329(-) (sepM) [Lactococcus cremoris strain 3107]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=307382 L3107_RS11625 WP_011677213.1 2250298..2251329(-) (sepM) [Lactococcus cremoris strain 3107]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTATGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49