Detailed information NTG0306411

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DK878_RS08190
• Genome accession: NZ_CP031379
• Coordinates: 1657730..1658779 (-)
• Length: 349 a.a.
• NCBI ID: WP_009910567.1
• Uniprot ID: A0A7Y6RPS3
• Organism: Streptococcus suis strain ISU2660
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1652730..1663779

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK878_RS08170 (DK878_08420)	nadE	1653558..1654382 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
DK878_RS08175 (DK878_08425)	-	1655256..1655783 (-)	528	WP_004194600.1	VanZ family protein	-
DK878_RS08180 (DK878_08430)	rlmN	1655780..1656892 (-)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DK878_RS08185 (DK878_08435)	-	1656901..1657542 (-)	642	WP_004194595.1	YutD-like domain-containing protein	-
DK878_RS08190 (DK878_08440)	sepM	1657730..1658779 (-)	1050	WP_009910567.1	SepM family pheromone-processing serine protease	Regulator
DK878_RS08195 (DK878_08445)	coaD	1658766..1659254 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
DK878_RS08200 (DK878_08450)	rsmD	1659244..1659783 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DK878_RS08205 (DK878_08455)	-	1660082..1660804 (-)	723	WP_013730502.1	hypothetical protein	-
DK878_RS08210 (DK878_08460)	-	1660861..1661247 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
DK878_RS08215 (DK878_08465)	-	1661247..1661465 (-)	219	WP_004194736.1	YqgQ family protein	-
DK878_RS08220 (DK878_08470)	-	1661765..1662367 (-)	603	WP_004194738.1	response regulator transcription factor	-
DK878_RS08225 (DK878_08475)	-	1662364..1663458 (-)	1095	WP_053866080.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37733.77 Da
• Isoelectric Point: 4.6112

>NTDB_id=306411 DK878_RS08190 WP_009910567.1 1657730..1658779(-) (sepM) [Streptococcus suis strain ISU2660]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLVKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=306411 DK878_RS08190 WP_009910567.1 1657730..1658779(-) (sepM) [Streptococcus suis strain ISU2660]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGGTTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A7Y6RPS3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.519	99.427	0.602