Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SPCG_RS10110 Genome accession   NC_010582
Coordinates   1915582..1916406 (-) Length   274 a.a.
NCBI ID   WP_001036788.1    Uniprot ID   -
Organism   Streptococcus pneumoniae CGSP14     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1910582..1921406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPCG_RS10105 (SPCG_1928) - 1913960..1915291 (-) 1332 WP_000390043.1 hemolysin family protein -
  SPCG_RS10110 (SPCG_1929) endA 1915582..1916406 (-) 825 WP_001036788.1 DNA-entry nuclease EndA Machinery gene
  SPCG_RS10115 - 1916445..1916633 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  SPCG_RS10120 (SPCG_1930) murA 1916626..1917909 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SPCG_RS10125 - 1917933..1918163 (-) 231 WP_000250392.1 DUF1146 family protein -
  SPCG_RS10130 (SPCG_1931) sepM 1918221..1919258 (-) 1038 WP_000727272.1 SepM family pheromone-processing serine protease Regulator
  SPCG_RS10135 (SPCG_1932) coaD 1919242..1919730 (-) 489 WP_001280736.1 pantetheine-phosphate adenylyltransferase -
  SPCG_RS10140 (SPCG_1933) rsmD 1919720..1920259 (-) 540 WP_000706966.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SPCG_RS10145 (SPCG_1934) asnA 1920324..1921316 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 30014.72 Da        Isoelectric Point: 10.1700

>NTDB_id=30638 SPCG_RS10110 WP_001036788.1 1915582..1916406(-) (endA) [Streptococcus pneumoniae CGSP14]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLNQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLFPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=30638 SPCG_RS10110 WP_001036788.1 1915582..1916406(-) (endA) [Streptococcus pneumoniae CGSP14]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAATCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTATTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

97.81

100

0.978
  endA Streptococcus pneumoniae D39

97.81

100

0.978
  endA Streptococcus pneumoniae R6

97.81

100

0.978
  endA Streptococcus pneumoniae TIGR4

97.81

100

0.978

Multiple sequence alignment