Detailed information    

insolico Bioinformatically predicted

Overview

Name   radA   Type   Machinery gene
Locus tag   DK237_RS10060 Genome accession   NZ_CP031377
Coordinates   2001490..2002860 (-) Length   456 a.a.
NCBI ID   WP_004298358.1    Uniprot ID   A0A126UJP8
Organism   Streptococcus suis strain ISU2614     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2003407..2019008 2001490..2002860 flank 547


Gene organization within MGE regions


Location: 2001490..2019008
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK237_RS10060 (DK237_10355) radA 2001490..2002860 (-) 1371 WP_004298358.1 DNA repair protein RadA Machinery gene
  DK237_RS10065 (DK237_10360) - 2002867..2003400 (-) 534 WP_004298356.1 histidine phosphatase family protein -
  DK237_RS10070 (DK237_10365) - 2003407..2003850 (-) 444 WP_004298354.1 dUTP diphosphatase -
  DK237_RS10075 (DK237_10370) - 2003949..2005094 (-) 1146 WP_044752539.1 site-specific integrase -
  DK237_RS10080 (DK237_10375) - 2005630..2006157 (-) 528 WP_053861464.1 helix-turn-helix transcriptional regulator -
  DK237_RS10085 (DK237_10380) - 2006367..2006564 (+) 198 WP_053861463.1 helix-turn-helix transcriptional regulator -
  DK237_RS10090 (DK237_10385) - 2006583..2007326 (+) 744 WP_024417795.1 BRO family protein -
  DK237_RS10095 (DK237_10390) - 2007330..2007956 (+) 627 WP_053861462.1 Rha family transcriptional regulator -
  DK237_RS10100 (DK237_10395) - 2008445..2008807 (+) 363 WP_248029224.1 hypothetical protein -
  DK237_RS10105 (DK237_10400) - 2008795..2008992 (+) 198 WP_044752498.1 hypothetical protein -
  DK237_RS10110 (DK237_10405) - 2009002..2009187 (+) 186 WP_044752496.1 hypothetical protein -
  DK237_RS10115 (DK237_10410) - 2009184..2009522 (+) 339 WP_029178751.1 hypothetical protein -
  DK237_RS10120 (DK237_10415) - 2009512..2009796 (+) 285 WP_024417111.1 hypothetical protein -
  DK237_RS10125 (DK237_10420) - 2009964..2010434 (+) 471 WP_024394241.1 hypothetical protein -
  DK237_RS10130 (DK237_10425) - 2010431..2012029 (+) 1599 WP_002939056.1 hypothetical protein -
  DK237_RS10135 (DK237_10430) - 2012369..2012542 (+) 174 WP_002939058.1 sporulation protein Cse60 -
  DK237_RS10140 (DK237_10435) - 2012563..2013138 (+) 576 WP_053861459.1 hypothetical protein -
  DK237_RS10145 (DK237_10440) - 2013188..2013589 (+) 402 WP_172007689.1 hypothetical protein -
  DK237_RS10150 (DK237_10445) - 2013757..2014176 (+) 420 WP_053861433.1 hypothetical protein -
  DK237_RS10155 (DK237_10450) - 2014208..2014528 (+) 321 WP_161802164.1 DUF1492 domain-containing protein -
  DK237_RS10160 (DK237_10455) - 2015075..2016859 (-) 1785 WP_004298352.1 ABC transporter ATP-binding protein -
  DK237_RS10165 (DK237_10460) - 2016860..2018566 (-) 1707 WP_004298350.1 ABC transporter ATP-binding protein -
  DK237_RS10170 (DK237_10465) - 2018559..2019008 (-) 450 WP_004298348.1 MarR family winged helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 50002.51 Da        Isoelectric Point: 6.1911

>NTDB_id=306365 DK237_RS10060 WP_004298358.1 2001490..2002860(-) (radA) [Streptococcus suis strain ISU2614]
MTIAKKKTTFVCQSCEYHSPKYLGRCPNCGSWSSFVEEVEVAEVKNERVSLTGEKTRPMKLNEVSSIQVARTKTNMEEFN
RVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSTIGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSIRTE
IEKIKPDFLIIDSIQTIMSPDISSVQGSVSQVREVTNELMQIAKTNNIATFIVGHMTKEGTLAGPRTLEHMVDTVLYFEG
ERQHTFRILRAVKNRFGSTNEIGIFEMQSQGLVEVLNPSEVFLEERLDGATGSAIVVTMEGTRPILAEVQALVTPTMFGN
AKRTTTGLDFNRASLIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVALASSYKDKPTNPQECFIGEIGLTGE
IRRVNRIEQRINEAAKLGFTKVYAPKNSLTGIKVPKEITVISVTTIGEVLQKVFNL

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=306365 DK237_RS10060 WP_004298358.1 2001490..2002860(-) (radA) [Streptococcus suis strain ISU2614]
ATGACCATCGCTAAGAAAAAAACAACCTTTGTCTGTCAATCCTGCGAGTACCACTCGCCCAAGTATCTGGGCCGTTGCCC
CAACTGTGGCTCCTGGTCTAGCTTTGTCGAGGAAGTGGAAGTCGCTGAAGTCAAGAACGAGCGGGTCAGTCTGACAGGTG
AGAAGACCCGTCCTATGAAGCTCAATGAAGTGTCGTCCATTCAAGTGGCCCGCACCAAGACCAATATGGAAGAGTTTAAC
CGTGTCCTTGGTGGCGGCGTGGTGCCGGGCAGTCTGGTCCTGATTGGAGGCGATCCAGGGATTGGCAAATCGACCTTGCT
CCTGCAAGTATCGACCCAACTTTCGACTATTGGCACCGTCCTCTATGTGTCGGGGGAAGAGTCTGCCCAGCAGATTAAGT
TGCGAGCGGAGCGTTTGGGCGACATTGACAGCGAGTTCTATCTCTATGCGGAGACCAATATGCAGAGCATTCGGACTGAG
ATTGAGAAAATCAAGCCAGATTTCCTGATTATCGACTCTATCCAGACCATTATGAGCCCTGACATTTCTAGCGTGCAAGG
TTCTGTCAGTCAGGTCCGTGAAGTGACCAATGAGCTTATGCAGATTGCCAAGACCAACAATATCGCAACCTTTATCGTCG
GCCACATGACCAAGGAAGGCACCCTGGCTGGACCGCGGACCTTGGAGCACATGGTAGACACCGTTCTCTATTTTGAGGGC
GAGCGTCAACACACCTTCCGTATCTTGAGGGCGGTCAAAAATCGCTTTGGCTCCACCAACGAAATCGGTATTTTTGAAAT
GCAGTCGCAGGGCTTGGTCGAAGTTCTCAATCCAAGTGAGGTCTTTCTGGAAGAGCGTCTGGACGGAGCGACTGGCTCGG
CTATTGTCGTGACCATGGAGGGCACCCGCCCTATCCTTGCCGAAGTGCAGGCTCTGGTGACCCCGACCATGTTTGGCAAT
GCCAAGCGGACCACGACAGGCTTGGATTTCAACCGTGCCAGCTTGATTATGGCGGTTTTGGAAAAACGGGCCGGTCTGCT
CCTCCAAAACCAAGATGCCTACCTTAAGTCAGCAGGCGGTGTCAAACTGGATGAGCCAGCTATTGACCTAGCGGTCGCAG
TTGCCCTTGCCTCCAGTTACAAGGACAAGCCAACCAACCCACAAGAGTGCTTTATAGGCGAGATTGGCCTGACAGGGGAA
ATCCGCCGCGTCAATCGGATTGAACAACGGATTAACGAAGCCGCCAAATTGGGCTTTACCAAGGTCTATGCCCCAAAAAA
TTCCCTGACAGGTATCAAGGTGCCCAAGGAAATCACCGTTATCAGCGTGACCACCATTGGCGAAGTCTTGCAGAAAGTAT
TCAACTTATGA

Domains

Predicted by InterproScan.

Subunit ChlI of Mg-chelatase (ChlI)

(363-427)

Rubredoxin metal binding domain (Zn_ribbon_LapB)

(10-37)

AAA domain (AAA_25)

(64-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UJP8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  radA Streptococcus mitis NCTC 12261

91.15

99.123

0.904
  radA Streptococcus pneumoniae D39

90.929

99.123

0.901
  radA Streptococcus pneumoniae R6

90.929

99.123

0.901
  radA Streptococcus pneumoniae Rx1

90.929

99.123

0.901
  radA Streptococcus pneumoniae TIGR4

90.929

99.123

0.901
  radA Streptococcus mitis SK321

90.708

99.123

0.899
  radA Bacillus subtilis subsp. subtilis str. 168

62.472

99.342

0.621

Multiple sequence alignment