Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   DK237_RS01215 Genome accession   NZ_CP031377
Coordinates   221762..222475 (+) Length   237 a.a.
NCBI ID   WP_012774930.1    Uniprot ID   A0A142UPI2
Organism   Streptococcus suis strain ISU2614     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 195184..228278 221762..222475 within 0


Gene organization within MGE regions


Location: 195184..228278
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK237_RS01115 (DK237_01140) - 195184..195822 (+) 639 WP_002935979.1 endonuclease III domain-containing protein -
  DK237_RS01120 (DK237_01150) - 196105..197304 (-) 1200 WP_013730097.1 ROK family protein -
  DK237_RS01125 (DK237_01155) - 197496..198824 (+) 1329 WP_002935977.1 PTS sugar transporter subunit IIC -
  DK237_RS01130 (DK237_01160) - 198829..200715 (+) 1887 WP_002935976.1 DUF4838 domain-containing protein -
  DK237_RS01135 (DK237_01165) - 200835..203774 (+) 2940 WP_002935975.1 right-handed parallel beta-helix repeat-containing protein -
  DK237_RS01140 (DK237_01170) - 203989..204750 (+) 762 WP_002935974.1 hypothetical protein -
  DK237_RS01145 (DK237_01175) - 204972..205730 (+) 759 WP_002935973.1 ABC transporter permease -
  DK237_RS01150 (DK237_01180) - 205715..206506 (+) 792 WP_002935969.1 ABC transporter ATP-binding protein -
  DK237_RS01155 (DK237_01185) - 206537..207565 (+) 1029 WP_002935967.1 ABC transporter substrate-binding protein -
  DK237_RS01160 (DK237_01190) - 207659..208468 (+) 810 WP_002935966.1 hypothetical protein -
  DK237_RS11100 - 208641..210702 (+) 2062 Protein_199 heavy metal translocating P-type ATPase -
  DK237_RS01180 (DK237_01210) - 210741..213230 (-) 2490 WP_053861446.1 ATP-dependent RecD-like DNA helicase -
  DK237_RS01185 (DK237_01215) lepB 213295..213924 (-) 630 WP_024386967.1 signal peptidase I -
  DK237_RS01190 (DK237_01220) rnhC 213934..214824 (-) 891 WP_013730101.1 ribonuclease HIII -
  DK237_RS01195 (DK237_01225) - 214909..215892 (+) 984 WP_009909178.1 Gfo/Idh/MocA family protein -
  DK237_RS01200 (DK237_01235) - 216241..217416 (+) 1176 WP_013730102.1 LysM domain-containing protein -
  DK237_RS01205 (DK237_01240) treC 217829..219454 (-) 1626 WP_009909185.1 alpha,alpha-phosphotrehalase -
  DK237_RS01210 (DK237_01245) treP 219535..221529 (-) 1995 WP_002935953.1 PTS system trehalose-specific EIIBC component -
  DK237_RS01215 (DK237_01250) treR 221762..222475 (+) 714 WP_012774930.1 trehalose operon repressor Regulator
  DK237_RS01220 (DK237_01255) - 222533..222844 (+) 312 WP_002935948.1 hypothetical protein -
  DK237_RS01225 (DK237_01260) - 222841..223389 (+) 549 WP_002935945.1 CvpA family protein -
  DK237_RS01230 (DK237_01270) - 223940..226273 (+) 2334 WP_002935942.1 endonuclease MutS2 -
  DK237_RS01235 (DK237_01275) - 226439..226831 (+) 393 WP_014636774.1 DUF1310 family protein -
  DK237_RS01240 (DK237_01280) - 226824..227087 (+) 264 WP_022540536.1 hypothetical protein -
  DK237_RS01245 (DK237_01285) - 227113..227490 (+) 378 WP_002935940.1 DUF1310 family protein -
  DK237_RS01250 (DK237_01290) - 227537..227794 (+) 258 WP_002935939.1 hypothetical protein -
  DK237_RS01255 (DK237_01295) - 227889..228278 (+) 390 WP_002935938.1 DUF1310 family protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27200.07 Da        Isoelectric Point: 6.7422

>NTDB_id=306331 DK237_RS01215 WP_012774930.1 221762..222475(+) (treR) [Streptococcus suis strain ISU2614]
MKKYQEIYNDLKEKIRTNVYPAESSLPTEQQLQEIYGVSRDTVRKALAILTEGGLIQKVQGRGSMVLKQEILNFPVSGLT
SYQELTNVLQLSTKTDVVSLDMITVNSSLSHLTGFEPYSKVWKVVRTRSIDGKVSVVDTDYLAVDVVPELTTAIAEKSIY
EYLENKLGLDIAYAQKEITVEPTNREERELMQSKDDYLVLIKSRVYLGDTQQFQYTESKHKIDKFRFVDFARRKHSL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=306331 DK237_RS01215 WP_012774930.1 221762..222475(+) (treR) [Streptococcus suis strain ISU2614]
ATGAAAAAATACCAAGAAATTTATAATGACTTAAAAGAAAAAATACGGACAAATGTTTATCCGGCAGAAAGCTCCCTACC
GACAGAACAGCAGCTTCAGGAAATCTATGGTGTTAGTCGTGATACGGTTCGTAAGGCGTTGGCGATTTTGACTGAGGGAG
GTTTGATTCAAAAAGTGCAAGGGCGTGGTTCAATGGTCCTTAAGCAAGAAATTCTCAATTTCCCAGTTTCAGGTTTAACT
TCCTATCAGGAATTAACAAATGTTCTCCAGCTTTCTACCAAGACAGATGTTGTCAGCTTAGATATGATTACCGTTAATAG
TAGCCTTTCGCACTTGACAGGCTTTGAGCCGTATAGCAAGGTGTGGAAAGTTGTCCGTACACGTTCAATTGACGGTAAGG
TCTCCGTTGTGGATACAGATTATCTTGCTGTCGATGTCGTGCCAGAGTTGACAACTGCTATTGCTGAAAAATCCATCTAC
GAATACCTAGAAAATAAGTTAGGCCTTGATATTGCTTATGCACAAAAAGAGATTACGGTAGAGCCGACCAATCGAGAAGA
GCGTGAGCTAATGCAATCGAAGGATGATTATTTGGTCTTGATTAAATCTCGTGTCTATCTCGGTGATACCCAACAATTCC
AATATACAGAAAGCAAGCATAAAATTGATAAATTCCGCTTTGTAGATTTTGCTCGTAGAAAGCATTCTTTATAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A142UPI2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

52.137

98.734

0.515

Multiple sequence alignment