Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   DV166_RS08540 Genome accession   NZ_CP031334
Coordinates   1449128..1451347 (+) Length   739 a.a.
NCBI ID   WP_153063298.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22293     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 1444128..1456347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV166_RS08540 comA 1449128..1451347 (+) 2220 WP_153063298.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DV166_RS08545 comL 1451405..1452208 (-) 804 WP_002221259.1 outer membrane protein assembly factor BamD Machinery gene
  DV166_RS08550 rluD 1452207..1453331 (+) 1125 WP_002223935.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  DV166_RS08555 - 1453483..1454430 (-) 948 WP_002219577.1 bile acid:sodium symporter family protein -
  DV166_RS08565 pgeF 1454989..1455768 (+) 780 WP_115437078.1 peptidoglycan editing factor PgeF -
  DV166_RS08570 lptE 1455820..1456299 (+) 480 WP_002217671.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 739 a.a.        Molecular weight: 79892.49 Da        Isoelectric Point: 9.8955

>NTDB_id=305984 DV166_RS08540 WP_153063298.1 1449128..1451347(+) (comA) [Neisseria meningitidis strain M22293]
MFRRWFLPCWVVGAAASFALPVVPHWLFWLAAFAVFAVFARRFAFAGLMLCVLAGAAYGVFRTEAALSSQWWAEAVSGVP
LTVEVADMPRSDGRRVQFAAKAVDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGIGGA
GTVGADRVLLHGGSGWGIAVWRSRISRNWQQADADGGLSDGIGLMRALSVGEQSALRPELWQAFRPLGLTHLVSISGLHV
TMVAVMFAWLAKRLLACSPRLPARPRAWVLAAGCAGALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALA
AVLLFDPSAVLGVGTWLSFGLVAALIWACSGRLHEGKRQTALRGQWAASVLSLVLLGYLFASLPLVSPLVNAVAIPWFSW
VLTPLALLGSVVPFAPLQQLGAFLAEYTLRFLVWLADVSPEFAVASAPLPLLVLAVCAALLLLLPRGLGLRPWAVLLLAG
FVFYRSPGVPENEVAVTVWDAGQGLSVSVQTANHHLLFDTGTAAAAQMGIVPSLNASGIRYLDYLVLSHHDSDHDGGFQA
VGKIPNGGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLMPSERKNIDDNGKSCVLRVVAGGAALLVTGDLDTKGEESLVG
KYGGNLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYANAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGG
VKAQRLRGYKFYWQKKPFE

Nucleotide


Download         Length: 2220 bp        

>NTDB_id=305984 DV166_RS08540 WP_153063298.1 1449128..1451347(+) (comA) [Neisseria meningitidis strain M22293]
GTGTTCCGTCGTTGGTTTTTGCCGTGTTGGGTTGTCGGTGCGGCGGCTTCGTTCGCGCTGCCGGTCGTGCCGCATTGGCT
GTTTTGGCTGGCGGCTTTTGCGGTTTTTGCTGTGTTTGCAAGGCGTTTTGCGTTTGCCGGTCTGATGCTGTGCGTGTTGG
CGGGCGCGGCTTACGGCGTATTCAGGACGGAGGCGGCATTGTCTTCCCAATGGTGGGCAGAAGCCGTTTCAGGCGTGCCT
TTGACGGTGGAAGTGGCGGATATGCCGAGGTCGGACGGGCGGCGTGTGCAGTTTGCGGCAAAGGCTGTGGACAGCGGTGG
TCGGACGTTTGATTTGCTGCTGTCGGACTACAAACGGCGCGAATGGGCGGTCGGGAGCAGATGGCGGATAACGGCACGTG
TGCACCCTGTCGTCGGGGAGTTGAACCTGCGCGGTTTGAACCGTGAGGCGTGGGCATTATCCAACGGAATAGGCGGCGCG
GGGACGGTCGGTGCGGACAGGGTTTTGCTGCATGGCGGAAGCGGTTGGGGGATTGCGGTTTGGCGCAGCCGCATCAGCCG
TAATTGGCAGCAGGCGGATGCGGACGGCGGGCTTTCAGACGGCATCGGGCTGATGCGCGCGTTGAGCGTGGGCGAACAGT
CGGCATTGCGCCCCGAATTGTGGCAGGCGTTCCGGCCGTTGGGGCTGACGCATTTGGTCAGTATTTCGGGTTTGCACGTT
ACGATGGTGGCGGTAATGTTTGCGTGGCTGGCGAAGCGGCTGCTTGCCTGTTCCCCGCGCCTTCCTGCCCGGCCGCGCGC
GTGGGTTTTGGCGGCGGGGTGTGCAGGCGCGCTGTTTTACGCGCTGCTTGCCGGTTTTTCCGTGCCGACGCAGCGCAGCG
TTTTGATGTTGGCGGCGTTTGCGTGGGCTTGGCGCAGGGGAAGATTGTCGGCGTGGGCGACGTGGTGGCAGGCGTTGGCG
GCGGTGCTGCTGTTCGACCCGTCGGCGGTCTTGGGTGTGGGGACTTGGCTGTCTTTCGGTTTGGTGGCGGCCCTGATATG
GGCGTGCTCGGGGCGTTTGCACGAGGGAAAACGGCAAACTGCTTTGCGCGGGCAGTGGGCGGCTTCGGTGTTGTCGCTGG
TTTTGCTCGGTTATCTGTTTGCTTCGCTGCCTTTGGTCAGCCCTTTGGTCAATGCGGTGGCAATTCCGTGGTTTTCTTGG
GTATTGACGCCGCTGGCGTTGCTGGGTTCGGTCGTGCCGTTTGCGCCTTTGCAACAGTTGGGGGCATTTTTGGCGGAATA
TACTTTGCGGTTTTTGGTGTGGCTTGCCGATGTGTCGCCCGAGTTTGCCGTTGCCTCCGCACCTTTGCCGCTGTTGGTGT
TGGCGGTGTGTGCCGCTTTGCTGTTGCTGCTGCCGCGCGGCTTGGGTTTGCGTCCGTGGGCGGTGTTGCTGTTGGCAGGG
TTTGTGTTTTACCGTTCACCCGGCGTGCCGGAAAATGAGGTTGCGGTTACGGTTTGGGATGCGGGGCAGGGTTTGTCGGT
GTCGGTTCAGACGGCAAATCATCATCTTTTGTTTGACACCGGAACGGCAGCGGCGGCGCAGATGGGGATTGTGCCGAGCT
TGAATGCGTCGGGAATCAGGTATTTGGATTATTTGGTTTTGTCGCATCACGACAGCGACCACGACGGCGGTTTTCAGGCA
GTCGGCAAGATACCGAACGGCGGGATTTATGCCGGGCAGCCGGAATTTTATGAGGGGGCGCGGCATTGTGCGGAACAGCG
TTGGCAATGGGACGGCGTGGATTTTGAGTTTTTGATGCCGTCTGAACGCAAAAACATCGATGATAATGGGAAAAGTTGTG
TTTTGCGTGTTGTGGCGGGCGGTGCGGCACTGCTGGTAACGGGCGATTTGGATACGAAGGGCGAGGAAAGCCTGGTCGGC
AAGTATGGAGGCAACCTGTACAGCCAGGTTTTGGTTTTGGGACATCACGGCAGCAATACGTCCTCGTCGGGCGTGTTCCT
CAATGCCGTCTCGCCCGAATATGCCGTTGCTTCAAGCGGTTATGCCAACGCCTACAAACATCCGACCGAAGCGGTGCAGA
ACCGTGTCCGCGCACACGGCATCAAACTGCTGCGTACCGATTTGTCGGGCGCACTGCAATTCGGCTTGGGACGCGGCGGC
GTGAAGGCTCAACGTTTGAGAGGGTATAAATTCTATTGGCAGAAAAAACCGTTTGAATGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(208-465)

Domain of unknown function (DUF4131) (DUF4131)

(8-167)

Metallo-beta-lactamase superfamily (Lactamase_B)

(501-677)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

95.129

100

0.951

Multiple sequence alignment