Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV166_RS01930 Genome accession   NZ_CP031334
Coordinates   346194..349310 (+) Length   1038 a.a.
NCBI ID   WP_115436911.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22293     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 341194..354310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV166_RS01885 hpaC 341742..342242 (-) 501 WP_002233027.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  DV166_RS01890 nadR 342357..342797 (-) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  DV166_RS01900 - 343140..343649 (-) 510 WP_002244687.1 protein disulfide oxidoreductase -
  DV166_RS01910 apbC 344014..345093 (+) 1080 WP_025458860.1 iron-sulfur cluster carrier protein ApbC -
  DV166_RS01930 pilC 346194..349310 (+) 3117 WP_115436911.1 PilC family type IV pilus tip adhesin Machinery gene
  DV166_RS01965 carA 351871..353004 (+) 1134 WP_002223013.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  DV166_RS01970 - 353050..353187 (+) 138 WP_002214606.1 VOC family protein -
  DV166_RS01980 - 353748..354137 (+) 390 WP_002219820.1 endonuclease domain-containing protein -

Sequence

Protein


Download         Length: 1038 a.a.        Molecular weight: 113379.81 Da        Isoelectric Point: 9.7292

>NTDB_id=305962 DV166_RS01930 WP_115436911.1 346194..349310(+) (pilC) [Neisseria meningitidis strain M22293]
MNKTLKRQVFRHTALYTAILMFSHTGGGGAQAQTHKYAIIINERNQPEVKQNGQYSTIKDKYREREYTHHPSKGGGGSVS
FNNSDELVSRQSGTAVFGTATYLPPYGKVSGFDADGLEKRNNAVDWIRTTRIALAGYRYDNVVCRSTTDCPKLVYKTRFS
FDNPDLAKTGVGLDKHTEPSRDNSPIYKLKDHPWLGVSFNLGAEGTAKNGKTINKLVSSFNEKNSNNNLVYTTEGRDISL
GDWQRETTAMAYYLNAKLHLLDKKGIKDIAQGKTVDLGTLRPRVETTGRSWLNFWAKWDIKDNGQIPVKLGLPEVKAGRC
INKANPNPKAQALSPALTAPALWFGAGQDGKAEMYSASVSTYPDSSSSRIFLQNLKRKNDPNKPGRYSLADLSASDIQSK
EPTFTSRQTIIRLDGGVQQIKLDKSNEATGLNGNDGKNNTFGIVSEGSFTPDVSEWKKVLLPWTVRGSADDGRFKSINQE
SSKYSQRYRIRENGNNSKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRQYFDNDTSA
LKDSTLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLTKADSNNPTAVSLFDVKN
GNNGKNSNNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKDINNGDNKTALYVYDLESNNGTPIAKIEVPNGKGGL
SSPTLVDKDLDGTVDIAYAGDRGGSMYRFDLSGNNPTSWSARAIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEEDVD
SKEIQHVYGIFDNDTDTGTAQDGQGKGLLEQKLEKDKDGKTLFLSDYKRSDGSSDKGWVVKLEAGQRVTVKPTVVLRTAF
VTIHKYTGNDKCGAETAILGINTADGGKLTKKSARPIVPADNTAVAQYSGHKQTAKGKSIPIGCMEKNNGIVCPNGYVYD
KPVNVRYLDEKKTDGFSTTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3117 bp        

>NTDB_id=305962 DV166_RS01930 WP_115436911.1 346194..349310(+) (pilC) [Neisseria meningitidis strain M22293]
ATGAATAAAACTTTAAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATACCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGCAAACCCATAAATACGCTATTATCATAAACGAGCGAAACCAGCCCGAGGTAAAGCAGAATGGGC
AATATTCAACAATAAAGGACAAATACAGGGAGCGCGAATATACTCATCATCCGTCCAAAGGAGGAGGAGGCTCTGTCTCA
TTCAACAATAGCGATGAGCTTGTTTCTCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGACGGGCTGGAAAAGCGCAACAATGCCGTCGATTGGATTCGTACCACCCGCATCGCGC
TGGCAGGCTACAGATACGACAATGTCGTATGCAGAAGCACCACAGACTGTCCCAAACTTGTCTATAAAACCCGATTTTCC
TTCGATAATCCCGACTTGGCAAAAACAGGAGTCGGGCTGGATAAGCACACAGAGCCAAGCCGCGACAATTCGCCCATTTA
CAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGTGCCGAGGGTACCGCCAAAAATGGTAAGACAATCA
ACAAATTGGTATCTTCTTTTAATGAAAAGAATAGTAATAACAACCTCGTCTATACCACGGAAGGCCGCGATATTTCCTTG
GGCGACTGGCAGCGCGAAACGACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGGGATTAA
AGATATCGCCCAAGGCAAAACAGTGGATTTGGGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAAGCTGGCTAAATT
TTTGGGCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCGGAAGTCAAAGCAGGCCGCTGC
ATCAACAAAGCGAACCCCAATCCCAAAGCCCAAGCCCTTTCCCCCGCCTTGACCGCCCCCGCGCTGTGGTTCGGAGCTGG
GCAAGATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCTTCCTTCAAA
ATCTGAAAAGAAAAAACGACCCCAACAAACCCGGCCGCTATTCCCTCGCAGACTTGAGTGCGTCGGATATTCAAAGTAAA
GAGCCGACTTTCACAAGTCGGCAAACAATCATCCGATTGGATGGCGGCGTACAGCAGATCAAACTGGATAAAAGCAATGA
GGCCACCGGTTTAAATGGAAATGACGGCAAAAACAACACTTTCGGCATTGTTAGTGAAGGGAGCTTCACGCCTGATGTCA
GCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTTCTGCTGATGACGGTCGATTTAAATCAATTAACCAAGAA
TCAAGCAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAATAGCAAGCGTGATTTGGGCGACATCGTCAACAG
CCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAACAAAGCGGCGGGG
ACAAGCGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACTTCCGCT
CTCAAAGACTCCACCCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGG
CGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTGGGCG
GCAGAGGCGCGTATGCCTTGGATTTGACCAAAGCCGACAGCAATAACCCGACCGCCGTTTCCCTGTTTGATGTCAAAAAT
GGCAATAATGGCAAGAATAGCAATAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAA
AACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAGACATTAACAACGGCGACAATAAAACCG
CGCTGTATGTGTATGATTTGGAAAGCAACAACGGTACGCCGATTGCAAAAATCGAAGTACCCAACGGCAAGGGCGGGCTT
TCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTTGATATCGCCTATGCCGGCGATCGCGGCGGCAGTATGTA
CCGCTTTGATTTAAGCGGCAACAACCCGACCAGTTGGTCTGCACGCGCCATTTTCAGCGGCAACAAACCGATTACTTCCG
CGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAAGAGGATGTGGAC
AGCAAAGAAATCCAACACGTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAAAGG
GCTGCTCGAGCAAAAGCTGGAAAAAGACAAAGACGGCAAAACGCTGTTTTTAAGCGACTACAAAAGGTCTGACGGCTCGA
GCGACAAGGGCTGGGTAGTGAAATTGGAAGCCGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTT
GTAACCATCCATAAATATACGGGTAATGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGG
CAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGCCGACAATACGGCTGTCGCGCAATATTCCGGTCATAAGCAAA
CCGCCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAAACAATGGAATCGTCTGCCCGAACGGATATGTTTACGAC
AAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAG
CGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGA
ACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(501-845)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

76.762

100

0.776

Multiple sequence alignment