Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV155_RS04290 Genome accession   NZ_CP031326
Coordinates   742095..745196 (+) Length   1033 a.a.
NCBI ID   WP_115431791.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M21374     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 737095..750196
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV155_RS04250 murU 737396..738091 (-) 696 WP_115431790.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -
  DV155_RS04255 hpaC 738107..738607 (-) 501 WP_002221506.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  DV155_RS04260 nadR 738722..739162 (-) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  DV155_RS04270 - 739505..740014 (-) 510 WP_002221509.1 protein disulfide oxidoreductase -
  DV155_RS04280 apbC 740379..741458 (+) 1080 WP_002234293.1 iron-sulfur cluster carrier protein ApbC -
  DV155_RS04290 pilC 742095..745196 (+) 3102 WP_115431791.1 PilC family type IV pilus tip adhesin Machinery gene
  DV155_RS04310 carA 746472..747605 (+) 1134 WP_002217954.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  DV155_RS04315 - 747651..747788 (+) 138 WP_002214606.1 VOC family protein -
  DV155_RS04330 - 748368..748757 (+) 390 WP_002221514.1 endonuclease domain-containing protein -
  DV155_RS13375 - 748761..748928 (+) 168 WP_153312129.1 hypothetical protein -
  DV155_RS04340 - 749335..749898 (+) 564 WP_002214615.1 phosphoribosyltransferase family protein -

Sequence

Protein


Download         Length: 1033 a.a.        Molecular weight: 113069.88 Da        Isoelectric Point: 9.7812

>NTDB_id=305688 DV155_RS04290 WP_115431791.1 742095..745196(+) (pilC) [Neisseria meningitidis strain M21374]
MNKTLKRQVFRHTALYAAILMFSHTGGGAQAETHNYAIVMNEQNQLKVKQKGSYSTLREKDRERKFIYNKSRQGGGSVFF
DNTDTLVSRQSGTAVFGTATYLPPYGKVSGFDANALKERNNAVDWIHTTRAGLAGYAYTNVVCRSHQCPQLVYKTRFSFD
NPDLAKRGGGLDRHTEPSRDNSLIYKLKDHPWLGVSFNLGSENTVKNSQSSSRLISSFSEDNNNQTIVSTTENHPISLGD
RQREHTAVAYYLNAKLHLLDKKGIKDITGKTVRLGVLKPSIDVKTQRTGLGGLLGFHAKWDIKDTGQIPVELGLPQIKAG
RCINKPNPNPKAQALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSLKPLSTSEIK
SKEPTFTGRQTVIRLDGGVQQIKLQGNEVTSFNVNNGNNTFGIVKDLGVDPDASEWKKVLLPWTVRASNDDNQFKTINQQ
KIQYSQRYRIRDNGNRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRQYFDNDTSALKD
STLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLTKADSNNPTAVSLFDVKNGNN
GNNSNNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKTIDDQQNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPT
LVDKDLDGIVDIAYAGDRGGNMYRFDLSSDNPSSWTVRTIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDKTDE
QYIYGIFDDDTATTGPVNFSGTGGGLLEQVLTEENKTLFLTDYKRSDGSGSKGWVVKLKDGQRVTVKPTVVLRTAFVTIR
KYKDNGCGAETAILGINTADGGKLTKKSARPIVPADNTAVAQYSGHKQTTKGKSIPIGCMEKDNGIVCPNGYVYDKPVNV
RYLDEKKTDGFSTTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3102 bp        

>NTDB_id=305688 DV155_RS04290 WP_115431791.1 742095..745196(+) (pilC) [Neisseria meningitidis strain M21374]
ATGAATAAAACTTTAAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGGGG
GGGGGCGCAGGCGGAAACCCATAACTACGCTATTGTCATGAACGAACAAAATCAGCTGAAGGTAAAGCAGAAGGGTTCAT
ATTCAACCTTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATAATAAAAGCCGGCAGGGTGGAGGCTCTGTCTTTTTC
GACAATACCGATACCCTTGTTTCCCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGGCAA
GGTTTCCGGTTTTGATGCCAACGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCATACCACCCGGGCCGGGCTGG
CAGGCTACGCCTACACCAACGTCGTATGCAGAAGCCACCAATGCCCCCAACTTGTCTATAAAACCCGATTTTCCTTCGAT
AATCCCGACTTGGCAAAAAGAGGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCGCGACAATTCGCTCATTTACAAATT
GAAGGATCATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATAGCCAATCATCCAGCAGAT
TGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAAACCACCCTATTTCCCTTGGCGAC
AGGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAAAGGGATTAAAGATAT
CACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGACACAAAGGACGGGGCTTGGCGGCTTGC
TAGGTTTTCATGCTAAGTGGGACATTAAAGATACCGGGCAGATTCCGGTCGAGCTCGGCCTGCCGCAAATCAAAGCAGGC
CGCTGCATCAACAAACCGAACCCCAATCCCAAAGCCCAAGCCCTTTCGCCGGCACTGACTGCCCCCGCGCTGTGGTTCGG
ACCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCAAATTTTCC
TGCAAAACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTACGTCGGAGATTAAA
AGTAAAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATGGCGGCGTACAGCAGATTAAACTTCAAGGCAA
TGAGGTCACTAGTTTTAATGTAAACAACGGCAACAACACTTTCGGCATTGTTAAGGACTTGGGCGTCGATCCTGATGCCA
GCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTCCAATGATGACAATCAATTTAAAACAATTAACCAACAA
AAAATCCAATACAGCCAAAGATACCGCATCCGCGACAACGGCAATCGCGATTTGGGCGACATCGTCAACAGCCCCATCGT
GGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAACAAAGCGGCGGGGACAAGCGCA
GCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACTTCCGCTCTCAAAGAC
TCCACCCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGT
CTTGCGCCGCATTACAGATGACCAAGACAAGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTGGGCGGCAGAGGCG
CGTATGCCTTGGATTTGACCAAAGCCGACAGCAATAACCCGACCGCCGTTTCCCTGTTTGATGTCAAAAATGGCAATAAT
GGCAATAATAGCAATAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAA
CGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACGACCAACAAAATAAAACCGCGCTGTATG
TGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACG
CTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGATTT
GAGCAGCGACAATCCGTCCAGCTGGACTGTACGCACTATTTTCAGCGGCAACAAACCGATTACTTCCGCGCCCGCCATTT
CCCAACTGAAAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAGGATGATGTTGATAAAACGGACGAA
CAATATATTTACGGTATCTTTGACGACGATACGGCGACGACGGGTCCTGTAAACTTCAGCGGTACGGGAGGCGGGCTGCT
CGAGCAAGTGCTTACTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCGACGGCTCGGGCAGCAAAGGGT
GGGTAGTGAAATTGAAGGACGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGC
AAATATAAAGACAACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAA
AAGCGCGCGCCCGATTGTGCCGGCCGACAATACGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGGCAAAT
CCATCCCTATAGGTTGTATGGAAAAAGACAATGGAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTG
CGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGAACATTCAAAGA
AGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCT
TGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(498-841)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

77.355

100

0.787

Multiple sequence alignment