Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   DWB94_RS00185 Genome accession   NZ_CP031277
Coordinates   38068..39429 (-) Length   453 a.a.
NCBI ID   WP_145423854.1    Uniprot ID   -
Organism   Staphylococcus hominis strain 19A     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 26842..41063 38068..39429 within 0


Gene organization within MGE regions


Location: 26842..41063
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DWB94_RS00115 (DWB94_00115) - 26851..27633 (+) 783 WP_029376799.1 MBL fold metallo-hydrolase -
  DWB94_RS00120 (DWB94_00120) rlmH 28054..28533 (+) 480 WP_145423863.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DWB94_RS00125 (DWB94_00125) - 28625..29185 (+) 561 WP_145423862.1 hypothetical protein -
  DWB94_RS00130 (DWB94_00130) - 29305..29415 (+) 111 Protein_23 hypothetical protein -
  DWB94_RS00135 (DWB94_00135) - 29441..30658 (+) 1218 WP_145426883.1 restriction endonuclease subunit S -
  DWB94_RS00140 (DWB94_00140) - 30969..31466 (-) 498 WP_002473145.1 GNAT family N-acetyltransferase -
  DWB94_RS00145 (DWB94_00145) - 31645..33357 (-) 1713 WP_145426885.1 IS1182 family transposase -
  DWB94_RS00150 (DWB94_00150) - 33653..33874 (-) 222 WP_002473151.1 hypothetical protein -
  DWB94_RS00155 (DWB94_00155) - 33889..34392 (-) 504 WP_145423860.1 DUF1643 domain-containing protein -
  DWB94_RS00160 (DWB94_00160) - 34412..34723 (-) 312 WP_145423858.1 DUF960 domain-containing protein -
  DWB94_RS00170 (DWB94_00170) - 34810..35160 (-) 351 WP_002473147.1 SAUGI family uracil-DNA glycosylase inhibitor -
  DWB94_RS00175 (DWB94_00175) - 35702..36319 (-) 618 WP_145423856.1 hypothetical protein -
  DWB94_RS00180 (DWB94_00180) ccrB 36446..38071 (-) 1626 Protein_32 cassette chromosome recombinase CcrB -
  DWB94_RS00185 (DWB94_00185) ccrA 38068..39429 (-) 1362 WP_145423854.1 cassette chromosome recombinase CcrA Machinery gene
  DWB94_RS00190 (DWB94_00190) - 39616..40245 (-) 630 Protein_34 hypothetical protein -
  DWB94_RS00195 (DWB94_00195) - 40254..40592 (+) 339 Protein_35 recombinase family protein -
  DWB94_RS00200 (DWB94_00200) - 40704..41063 (-) 360 WP_049379424.1 hypothetical protein -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 53165.03 Da        Isoelectric Point: 9.6989

>NTDB_id=305372 DWB94_RS00185 WP_145423854.1 38068..39429(-) (ccrA) [Staphylococcus hominis strain 19A]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSHVTFYDDKKTGRHTKRSGYRKMVEMITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHVTIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTRNGIREKAKQGKLITTHAPFGYRYR
QGHFVVHEEEAYTVKAVYRWYLQGLGYKKISQHLDNNPKLTPRKPYQVRNILLNPNYCGRVINKYGTFNDLVPSIVDIDT
FEQAQQRRLNKHHKQHISENKLKKLLKCPYCQSTLTNLTIKKEHHSLRYYVCPKNMNEAYHTCPFKGINAQVIETEVLNT
CKAYCDNQSFHDKLNETILKALKHQQMKHRQSHLTQEQLIEKLAQNQIDIETFKRLSAGFEREERYSNYSSNQIAETIRH
VVKDKLTLEIIAPLIDDITITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=305372 DWB94_RS00185 WP_145423854.1 38068..39429(-) (ccrA) [Staphylococcus hominis strain 19A]
ATGGAAGAAGCCATTGCTTACGTACGTCAAAGTACATTAAAACAACAAAGCTTAGCGACACAGAAATCACTTATTATGGA
TACTGCTAAACAATATGGATGGTCTCATGTGACGTTTTATGATGATAAAAAAACAGGTCGACATACAAAACGTTCGGGCT
ATCGAAAAATGGTAGAAATGATTACATCTGGAAAATGTAAAGTATTATGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACGTCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGCTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGTGAAC
AGACACGAAATGGGATAAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCACCTTTTGGCTATCGTTATAGA
CAAGGTCATTTTGTTGTACATGAAGAAGAAGCGTATACAGTCAAAGCTGTCTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAAATTTCCCAACATTTAGATAACAATCCTAAGCTTACTCCACGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAGTATGGAACATTTAATGATTTAGTACCTTCTATTGTCGACATTGATACC
TTTGAACAAGCACAGCAACGTCGCTTGAATAAACATCATAAACAACACATTTCTGAAAACAAATTAAAGAAGCTACTTAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACAATAAAAAAAGAACATCATTCTCTACGTTACTATGTCTGTCCTA
AAAATATGAATGAAGCCTATCATACGTGTCCATTTAAAGGTATCAATGCGCAAGTGATTGAAACAGAGGTCCTCAACACT
TGTAAAGCATATTGTGACAATCAGTCATTTCATGACAAATTAAATGAGACAATACTAAAAGCTCTAAAACACCAACAAAT
GAAACACAGACAATCACATCTAACACAAGAACAACTCATCGAAAAACTGGCACAAAATCAAATTGATATCGAAACATTTA
AACGCTTATCTGCTGGCTTTGAAAGAGAAGAACGTTACTCTAATTATTCATCCAATCAAATTGCTGAAACAATCCGTCAT
GTAGTCAAAGATAAATTGACATTAGAAATCATAGCACCTTTGATTGATGACATTACAATAACTCAAACTAAACAGTTACA
AGGAATCTACTTTAAAAATAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA

Domains

Predicted by InterproScan.

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Recombinase (Recombinase)

(168-248)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

54.853

97.792

0.536
  ccrA Staphylococcus aureus N315

53.047

97.792

0.519

Multiple sequence alignment