Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DWB87_RS10295 Genome accession   NZ_CP031265
Coordinates   2028005..2028721 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 13     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2023005..2033721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DWB87_RS10265 (DWB87_10470) - 2023221..2023847 (+) 627 WP_000522384.1 nitroreductase family protein -
  DWB87_RS10270 (DWB87_10475) - 2024208..2024993 (+) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  DWB87_RS14065 hld 2025592..2025672 (-) 81 WP_000046023.1 delta-hemolysin -
  DWB87_RS10280 (DWB87_10485) - 2025962..2026525 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  DWB87_RS10285 (DWB87_10490) agrD 2026529..2026669 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  DWB87_RS10290 (DWB87_10495) agrC 2026694..2027986 (+) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  DWB87_RS10295 (DWB87_10500) agrA 2028005..2028721 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  DWB87_RS10300 (DWB87_10505) - 2028793..2028902 (+) 110 Protein_1943 hypothetical protein -
  DWB87_RS10305 (DWB87_10510) - 2029090..2030049 (-) 960 WP_001253302.1 carbohydrate kinase -
  DWB87_RS10310 (DWB87_10515) - 2030046..2031530 (-) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  DWB87_RS10315 (DWB87_10520) - 2031679..2032629 (-) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=305241 DWB87_RS10295 WP_000688492.1 2028005..2028721(+) (agrA) [Staphylococcus aureus strain 13]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=305241 DWB87_RS10295 WP_000688492.1 2028005..2028721(+) (agrA) [Staphylococcus aureus strain 13]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment