Detailed information NTG0305240

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DWB87_RS09740
• Genome accession: NZ_CP031265
• Coordinates: 1925791..1926834 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 13
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1920791..1931834

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DWB87_RS09710 (DWB87_09905)	-	1921219..1922475 (-)	1257	WP_001793428.1	aminopeptidase	-
DWB87_RS09715 (DWB87_09910)	-	1922478..1922678 (-)	201	WP_000180460.1	DUF1128 family protein	-
DWB87_RS09720 (DWB87_09915)	-	1922825..1923289 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
DWB87_RS09725 (DWB87_09920)	-	1923296..1923571 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
DWB87_RS09730 (DWB87_09925)	-	1923849..1925060 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
DWB87_RS09735 (DWB87_09930)	vraR	1925172..1925801 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
DWB87_RS09740 (DWB87_09935)	vraS	1925791..1926834 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
DWB87_RS09745 (DWB87_09940)	liaF	1926831..1927532 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
DWB87_RS09750 (DWB87_09945)	-	1927547..1927933 (-)	387	WP_001110179.1	hypothetical protein	-
DWB87_RS09755 (DWB87_09950)	map	1928150..1928908 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
DWB87_RS09760 (DWB87_09955)	-	1929324..1930310 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
DWB87_RS09765 (DWB87_09965)	-	1930741..1931154 (-)	414	WP_001837236.1	hypothetical protein	-
DWB87_RS09770 (DWB87_09970)	-	1931183..1931294 (-)	112	Protein_1838	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=305240 DWB87_RS09740 WP_001017131.1 1925791..1926834(-) (vraS) [Staphylococcus aureus strain 13]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=305240 DWB87_RS09740 WP_001017131.1 1925791..1926834(-) (vraS) [Staphylococcus aureus strain 13]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTAAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1