Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV389_RS04515 Genome accession   NZ_CP031250
Coordinates   912307..913527 (-) Length   406 a.a.
NCBI ID   WP_114893220.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M21384     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 907307..918527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV389_RS04475 (DV389_04475) - 908213..908419 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DV389_RS04480 (DV389_04480) - 908493..908699 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DV389_RS04485 (DV389_04485) - 908773..908979 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DV389_RS04490 (DV389_04490) - 909054..909260 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DV389_RS04495 (DV389_04495) cueR 909337..909723 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DV389_RS04500 (DV389_04500) metJ 909737..910054 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DV389_RS04505 (DV389_04505) rho 910302..911564 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  DV389_RS04510 (DV389_04510) - 911618..912310 (-) 693 Protein_852 A24 family peptidase -
  DV389_RS04515 (DV389_04515) pilC 912307..913527 (-) 1221 WP_114893220.1 type II secretion system F family protein Machinery gene
  DV389_RS04520 (DV389_04520) - 913524..914921 (-) 1398 Protein_854 GspE/PulE family protein -
  DV389_RS04525 (DV389_04525) pilA 914918..915367 (-) 450 WP_114893221.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DV389_RS04530 (DV389_04530) ampD 915481..916035 (+) 555 WP_114893222.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DV389_RS04535 (DV389_04535) corC 916669..917568 (+) 900 WP_005662987.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46308.56 Da        Isoelectric Point: 9.9102

>NTDB_id=304956 DV389_RS04515 WP_114893220.1 912307..913527(-) (pilC) [Haemophilus influenzae strain M21384]
MTKKLFYYQASNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIVLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKRIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQIKKTLVNDIILDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=304956 DV389_RS04515 WP_114893220.1 912307..913527(-) (pilC) [Haemophilus influenzae strain M21384]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTGTACTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTTCCGTTGTTTGTAAAAGAATAGCCACACATCGCAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCGGAGTTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATCTAAAACGTCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAATCAAGAAAACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCTGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

98.522

100

0.985
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.973
  pilC Glaesserella parasuis strain SC1401

38.155

98.768

0.377

Multiple sequence alignment