Detailed information NTG0304875

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DV130_RS09740
• Genome accession: NZ_CP031248
• Coordinates: 1802932..1803969 (+)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: A0AAQ2ZXI6
• Organism: Streptococcus pneumoniae strain M26365
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1797932..1808969

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV130_RS09700	yidC	1797967..1798893 (-)	927	WP_000835955.1	membrane protein insertase YidC	-
DV130_RS09705	-	1798971..1799249 (-)	279	WP_114865198.1	acylphosphatase	-
DV130_RS09710	-	1799283..1800023 (+)	741	WP_000152678.1	RNA methyltransferase	-
DV130_RS09715	-	1800079..1800762 (+)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
DV130_RS09725	asnA	1800874..1801866 (+)	993	WP_000747993.1	aspartate--ammonia ligase	-
DV130_RS09730	rsmD	1801931..1802470 (+)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DV130_RS09735	coaD	1802460..1802948 (+)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
DV130_RS09740	sepM	1802932..1803969 (+)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
DV130_RS09745	-	1804027..1804257 (+)	231	WP_078130841.1	DUF1146 family protein	-
DV130_RS09750	murA	1804281..1805564 (+)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DV130_RS09755	-	1805557..1805745 (+)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
DV130_RS09760	endA	1805784..1806608 (+)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
DV130_RS09765	-	1806899..1808230 (+)	1332	WP_000390039.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=304875 DV130_RS09740 WP_000727276.1 1802932..1803969(+) (sepM) [Streptococcus pneumoniae strain M26365]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=304875 DV130_RS09740 WP_000727276.1 1802932..1803969(+) (sepM) [Streptococcus pneumoniae strain M26365]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588