Detailed information NTG0304800

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DV129_RS09650
• Genome accession: NZ_CP031247
• Coordinates: 1768408..1769445 (+)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: A0AAQ2ZXI6
• Organism: Streptococcus pneumoniae strain M23734
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1763408..1774445

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV129_RS09610	yidC	1763444..1764370 (-)	927	WP_000835941.1	membrane protein insertase YidC	-
DV129_RS09615	-	1764448..1764726 (-)	279	WP_001174613.1	acylphosphatase	-
DV129_RS09620	-	1764760..1765500 (+)	741	WP_000152700.1	RNA methyltransferase	-
DV129_RS09625	-	1765556..1766239 (+)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
DV129_RS09635	asnA	1766350..1767342 (+)	993	WP_000747993.1	aspartate--ammonia ligase	-
DV129_RS09640	rsmD	1767407..1767946 (+)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DV129_RS09645	coaD	1767936..1768424 (+)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
DV129_RS09650	sepM	1768408..1769445 (+)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
DV129_RS09655	-	1769503..1769733 (+)	231	WP_000250392.1	DUF1146 family protein	-
DV129_RS09660	murA	1769757..1771040 (+)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DV129_RS09665	-	1771033..1771221 (+)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
DV129_RS09670	endA	1771260..1772084 (+)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
DV129_RS09675	-	1772375..1773706 (+)	1332	WP_000390039.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=304800 DV129_RS09650 WP_000727276.1 1768408..1769445(+) (sepM) [Streptococcus pneumoniae strain M23734]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=304800 DV129_RS09650 WP_000727276.1 1768408..1769445(+) (sepM) [Streptococcus pneumoniae strain M23734]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588