Detailed information NTG0304762

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: DV129_RS05270
• Genome accession: NZ_CP031247
• Coordinates: 982865..985018 (+)
• Length: 717 a.a.
• NCBI ID: WP_000205160.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain M23734
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 977865..990018

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV129_RS05205	-	977865..978476 (-)	612	WP_000394048.1	type II CAAX endopeptidase family protein	-
DV129_RS05215	blpZ	978627..978860 (-)	234	WP_000276498.1	immunity protein BlpZ	-
DV129_RS05220	-	978902..979591 (-)	690	WP_000760532.1	CPBP family intramembrane glutamic endopeptidase	-
DV129_RS05225	-	979643..980026 (-)	384	WP_000877381.1	hypothetical protein	-
DV129_RS05235	-	980655..980974 (-)	320	Protein_994	immunity protein	-
DV129_RS05245	-	981494..981613 (-)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-
DV129_RS05250	cipB	981717..981866 (-)	150	WP_001809846.1	bacteriocin-like peptide BlpO	Regulator
DV129_RS05260	blpN	982110..982313 (-)	204	WP_001099490.1	two-peptide bacteriocin subunit BlpN	-
DV129_RS05265	blpM	982329..982583 (-)	255	WP_001093255.1	two-peptide bacteriocin subunit BlpM	-
DV129_RS05270	comA/nlmT	982865..985018 (+)	2154	WP_000205160.1	peptide cleavage/export ABC transporter BlpA	Regulator
DV129_RS05275	-	985029..986390 (+)	1362	WP_001069063.1	bacteriocin secretion accessory protein	-
DV129_RS05280	blpC	986447..986602 (+)	156	WP_000358812.1	quorum-sensing system pheromone BlpC	-
DV129_RS05285	-	986646..987986 (-)	1341	WP_001099894.1	sensor histidine kinase	-
DV129_RS05290	comE/blpR	988000..988737 (-)	738	WP_001219137.1	LytTR family DNA-binding domain-containing protein	Regulator
DV129_RS05295	-	988742..989080 (-)	339	WP_000682136.1	LytTR family DNA-binding domain-containing protein	-
DV129_RS05300	-	989357..989686 (+)	330	WP_000132583.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80834.87 Da
• Isoelectric Point: 7.9743

>NTDB_id=304762 DV129_RS05270 WP_000205160.1 982865..985018(+) (comA/nlmT) [Streptococcus pneumoniae strain M23734]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLNQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=304762 DV129_RS05270 WP_000205160.1 982865..985018(+) (comA/nlmT) [Streptococcus pneumoniae strain M23734]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCTAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGGCCTGTTCAAGCAGATAAAACTCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATCGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGAGCTTTTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGGCATATTTCCATCAATTATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTAACCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.028	99.721	0.718
comA	Streptococcus mitis NCTC 12261	66.48	99.442	0.661
comA	Streptococcus mitis SK321	66.199	99.442	0.658
comA	Streptococcus pneumoniae Rx1	66.199	99.442	0.658
comA	Streptococcus pneumoniae D39	66.199	99.442	0.658
comA	Streptococcus pneumoniae R6	66.199	99.442	0.658
comA	Streptococcus pneumoniae TIGR4	65.919	99.442	0.656
comA	Streptococcus gordonii str. Challis substr. CH1	65.181	100	0.653