Detailed information NTG0304665

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: DV131_RS00575
• Genome accession: NZ_CP031246
• Coordinates: 105685..106344 (+)
• Length: 219 a.a.
• NCBI ID: WP_114865807.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain M26368
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 100685..111344

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV131_RS00540	mgaSpn	101294..102775 (-)	1482	WP_001205280.1	virulence factor transcriptional regulator MgaSpn	-
DV131_RS00545	-	103159..103383 (+)	225	WP_223200767.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
DV131_RS00550	amaP	103467..104033 (+)	567	WP_000030213.1	alkaline shock response membrane anchor protein AmaP	-
DV131_RS00555	-	104045..104215 (+)	171	WP_000455066.1	DUF2273 domain-containing protein	-
DV131_RS00560	-	104254..104862 (+)	609	WP_000064115.1	Asp23/Gls24 family envelope stress response protein	-
DV131_RS00565	-	104893..105096 (+)	204	WP_000109956.1	CsbD family protein	-
DV131_RS00570	-	105169..105615 (-)	447	WP_000155416.1	GNAT family protein	-
DV131_RS00575	cclA/cilC	105685..106344 (+)	660	WP_114865807.1	A24 family peptidase	Machinery gene
DV131_RS00580	-	106396..107547 (-)	1152	WP_050096570.1	XRE family transcriptional regulator	-
DV131_RS00585	-	107562..108293 (-)	732	WP_000934017.1	hypothetical protein	-
DV131_RS11425	-	108522..108623 (+)	102	Protein_111	prepilin peptidase	-
DV131_RS00595	trpA	108595..109371 (-)	777	WP_001126998.1	tryptophan synthase subunit alpha	-
DV131_RS00600	trpB	109364..110587 (-)	1224	WP_000331293.1	tryptophan synthase subunit beta	-
DV131_RS00605	-	110565..111164 (-)	600	WP_000169894.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24835.94 Da
• Isoelectric Point: 7.6418

>NTDB_id=304665 DV131_RS00575 WP_114865807.1 105685..106344(+) (cclA/cilC) [Streptococcus pneumoniae strain M26368]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=304665 DV131_RS00575 WP_114865807.1 105685..106344(+) (cclA/cilC) [Streptococcus pneumoniae strain M26368]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	98.174	100	0.982
cclA/cilC	Streptococcus pneumoniae D39	98.174	100	0.982
cclA/cilC	Streptococcus pneumoniae R6	98.174	100	0.982
cclA/cilC	Streptococcus pneumoniae TIGR4	96.804	100	0.968
cclA/cilC	Streptococcus mitis SK321	92.694	100	0.927
cclA/cilC	Streptococcus mitis NCTC 12261	87.671	100	0.877