Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   DV390_RS06555 Genome accession   NZ_CP031242
Coordinates   1322399..1323736 (+) Length   445 a.a.
NCBI ID   WP_042594789.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M21460     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1317399..1328736
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV390_RS06530 - 1317464..1320058 (-) 2595 WP_042611819.1 penicillin-binding protein 1A -
  DV390_RS06535 comA 1320157..1320954 (+) 798 WP_013527435.1 pilus assembly protein PilM Machinery gene
  DV390_RS06540 comB 1320955..1321461 (+) 507 WP_038439363.1 competence protein ComB Machinery gene
  DV390_RS06545 comC 1321458..1321979 (+) 522 WP_005662592.1 competence protein ComC Machinery gene
  DV390_RS06550 comD 1321976..1322389 (+) 414 WP_042594787.1 pilus assembly protein PilP Machinery gene
  DV390_RS06555 comE 1322399..1323736 (+) 1338 WP_042594789.1 type IV pilus secretin PilQ family protein Machinery gene
  DV390_RS06560 - 1323749..1324435 (+) 687 WP_042594791.1 ComF family protein -
  DV390_RS06565 nfuA 1324511..1325107 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  DV390_RS06570 nudC 1325174..1325968 (+) 795 WP_042594793.1 NAD(+) diphosphatase -
  DV390_RS06575 - 1326004..1326594 (+) 591 WP_042594795.1 YjaG family protein -
  DV390_RS06580 - 1326734..1327006 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49181.52 Da        Isoelectric Point: 7.8654

>NTDB_id=304541 DV390_RS06555 WP_042594789.1 1322399..1323736(+) (comE) [Haemophilus influenzae strain M21460]
MKKYLLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTVEQLAFQQDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGIYYLNGSQSGKGEVAGNLTTNEPHLVSHTIKLHFAKASELMKSLTTGSGSLLSPAGSITFDDRSN
LLVIQDEPRFVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=304541 DV390_RS06555 WP_042594789.1 1322399..1323736(+) (comE) [Haemophilus influenzae strain M21460]
ATGAAGAAATATCTTTTAAAGTGCGGTTATTTTTTAGTATGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACAGTGGAGCAATTAGCTTTTCAACAAGATG
TGAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGGATTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TGAAGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTGAGTCATACGATAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTCCTGCGGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTTTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTCACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGCAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.427

100

0.984
  comE Haemophilus influenzae Rd KW20

97.303

100

0.973
  comE Glaesserella parasuis strain SC1401

52.471

95.506

0.501
  pilQ Vibrio campbellii strain DS40M4

42.317

95.056

0.402
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.99

92.584

0.389
  pilQ Vibrio cholerae strain A1552

41.99

92.584

0.389

Multiple sequence alignment