Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV427_RS05365 Genome accession   NZ_CP031240
Coordinates   1063454..1064674 (-) Length   406 a.a.
NCBI ID   WP_114891561.1    Uniprot ID   -
Organism   Haemophilus haemolyticus strain M19345     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1058454..1069674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV427_RS05335 - 1060033..1060226 (-) 194 Protein_1003 cation transporter -
  DV427_RS05340 - 1060201..1060407 (-) 207 WP_114891558.1 heavy-metal-associated domain-containing protein -
  DV427_RS05345 - 1060484..1060870 (+) 387 WP_114891559.1 Cu(I)-responsive transcriptional regulator -
  DV427_RS05350 metJ 1060884..1061201 (-) 318 WP_005634287.1 met regulon transcriptional regulator MetJ -
  DV427_RS05355 rho 1061449..1062711 (+) 1263 WP_005629550.1 transcription termination factor Rho -
  DV427_RS05360 pilD 1062765..1063457 (-) 693 WP_114891560.1 prepilin peptidase Machinery gene
  DV427_RS05365 pilC 1063454..1064674 (-) 1221 WP_114891561.1 type II secretion system F family protein Machinery gene
  DV427_RS05370 pilB 1064671..1066065 (-) 1395 WP_114891562.1 GspE/PulE family protein Machinery gene
  DV427_RS05375 pilA 1066062..1066502 (-) 441 WP_114891563.1 prepilin peptidase-dependent pilin Machinery gene
  DV427_RS05380 ampD 1066617..1067171 (+) 555 WP_114891564.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DV427_RS05385 rppH 1067697..1068287 (+) 591 WP_005631202.1 RNA pyrophosphohydrolase -
  DV427_RS05390 - 1068287..1069084 (+) 798 WP_114891565.1 sulfite exporter TauE/SafE family protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46360.57 Da        Isoelectric Point: 9.9487

>NTDB_id=304476 DV427_RS05365 WP_114891561.1 1063454..1064674(-) (pilC) [Haemophilus haemolyticus strain M19345]
MNKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFTFSFFLFYYFYLKRQTWF
YQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGIPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSNSVSSELFPMEAQQMLQIGEQSGKLALMLEHIANNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=304476 DV427_RS05365 WP_114891561.1 1063454..1064674(-) (pilC) [Haemophilus haemolyticus strain M19345]
ATGAATAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAGGCAATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGCAAACTTTCCGTTGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGTTGTACCCATCAATGGTGCTGGGAATTTCACTATTACTAACACTCGCATTACTACTTTTTATCGTGCCTCAATT
TGCTGAAATGTATAGTGGCAATAATGCTGAGTTACCAACAATAACCGCAATATTGCTCTCTATATCTAATTTTCTTAAGC
AAAATATTGGGATTTTGCTATTTTTCACTTTTAGTTTTTTTCTATTTTATTACTTCTATCTAAAACGCCAGACCTGGTTT
TATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCATACCGCTTAATCAAGCGCTAGACAGTTTTCTCCCTCGTACACAAACGT
GGCAAACCAAGAAAACCCTCGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGAGCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGTGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCACATCGCGAATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTGATCATCGGAAGTCTGATTGGGATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGATCAGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

97.537

100

0.975
  pilC Haemophilus influenzae 86-028NP

97.044

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.653

98.768

0.382

Multiple sequence alignment