Detailed information NTG0303996

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: DV527_RS00245
• Genome accession: NZ_CP031196
• Coordinates: 50952..52301 (-)
• Length: 449 a.a.
• NCBI ID: WP_145437297.1
• Uniprot ID: -
• Organism: Staphylococcus saprophyticus strain 1A
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	49778..57513	50952..52301	within	0

Gene organization within MGE regions

Location: 49778..57513

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV527_RS00245 (DV527_00245)	ccrA	50952..52301 (-)	1350	WP_145437297.1	cassette chromosome recombinase CcrA	Machinery gene
DV527_RS00250 (DV527_00250)	-	52472..52735 (-)	264	WP_145437299.1	hypothetical protein	-
DV527_RS00255 (DV527_00255)	-	52801..54591 (-)	1791	WP_145437301.1	cassette chromosome replicative helicase	-
DV527_RS00260 (DV527_00260)	-	54717..56147 (-)	1431	WP_145437303.1	DUF6038 family protein	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52346.01 Da
• Isoelectric Point: 9.9784

>NTDB_id=303996 DV527_RS00245 WP_145437297.1 50952..52301(-) (ccrA) [Staphylococcus saprophyticus strain 1A]
MKQAMGYLRQSTTKQQSLPAQKQAIKTLAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKAKQGKMITTHAPFGYHYH
NGTFTIDTVKAPTVKAVFNYYLQGYGYKKIAQYLEADDKFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEEAQVTRTQKQVKRKPSENQLKQKIKCPYCDSTLTNMTIRKKNHTLRYYVCPQNLNASRFVCEFKGINAQELEISVLTT
CQDFFQNQQLYSKINQTIQQRLKRQRDIETKTTLNHEQLIEKLAHGKIDAETFREQTQSLHQQSKPISSISAYQIQRAFQ
NIIQQRFTLNMLNPYIDVISITKNKTLAGIYFKNEPLNIVNQTTQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=303996 DV527_RS00245 WP_145437297.1 50952..52301(-) (ccrA) [Staphylococcus saprophyticus strain 1A]
ATGAAACAAGCAATGGGTTACTTACGTCAAAGTACAACAAAACAACAATCACTTCCGGCACAGAAACAAGCCATCAAGAC
ATTAGCTGAAAAACACAATATTCAACACATCACATTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGAAACGGTT
ACCAGCAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGCTATCGGCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTGTGCCAAAAATATCATGTTCATATCTTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTTAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCTGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAAACAAGGTAAAATGATTACAACACATGCACCCTTTGGGTATCACTATCAT
AATGGTACTTTCACGATAGACACAGTAAAAGCACCAACAGTAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATGATAAATTCATTAATCGTAAGCCCTATCAAGTGCGTAATATTATCCTTA
ACCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TACGAAGAAGCTCAAGTTACCCGAACTCAGAAACAAGTCAAACGTAAGCCGTCAGAAAACCAACTCAAACAAAAAATCAA
ATGTCCTTATTGTGATTCAACACTAACTAATATGACCATTAGAAAAAAGAACCATACATTACGTTATTACGTCTGTCCTC
AAAATTTGAATGCATCTCGTTTTGTCTGTGAATTCAAGGGGATCAACGCACAAGAATTAGAAATAAGTGTCTTAACGACT
TGTCAGGACTTCTTTCAGAACCAACAGCTGTATTCAAAAATTAACCAAACAATTCAACAACGACTCAAAAGACAAAGAGA
CATAGAAACTAAAACTACACTCAACCACGAACAGCTGATAGAAAAATTGGCCCACGGCAAAATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACATCAACAATCAAAACCTATATCATCAATCAGTGCGTATCAAATTCAAAGAGCTTTTCAA
AACATCATTCAACAACGTTTCACGTTAAACATGCTGAATCCCTATATTGATGTAATTAGTATTACTAAAAACAAAACCCT
TGCGGGGATCTATTTCAAAAATGAACCTCTAAACATTGTCAATCAAACGACGCAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (170-249)

• Resolvase, N terminal domain (Resolvase) (4-147)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus COL	93.541	100	0.935
ccrA	Staphylococcus aureus N315	75.501	100	0.755