Detailed information NTG0303640

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DU470_RS09920
• Genome accession: NZ_CP031131
• Coordinates: 1937537..1938580 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain E16SA093
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1932537..1943580

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DU470_RS09890 (DU470_09890)	-	1932959..1934215 (-)	1257	WP_001789555.1	aminopeptidase	-
DU470_RS09895 (DU470_09895)	-	1934218..1934418 (-)	201	WP_000180460.1	DUF1128 family protein	-
DU470_RS09900 (DU470_09900)	-	1934565..1935029 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
DU470_RS09905 (DU470_09905)	-	1935036..1935311 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
DU470_RS09910 (DU470_09910)	-	1935589..1936806 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
DU470_RS09915 (DU470_09915)	vraR	1936918..1937547 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
DU470_RS09920 (DU470_09920)	vraS	1937537..1938580 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
DU470_RS09925 (DU470_09925)	liaF	1938577..1939278 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
DU470_RS09930 (DU470_09930)	-	1939303..1939689 (-)	387	WP_001110179.1	hypothetical protein	-
DU470_RS09935 (DU470_09935)	map	1939906..1940664 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
DU470_RS09950 (DU470_09950)	-	1941192..1942178 (+)	987	WP_000999714.1	aromatic acid exporter family protein	-
DU470_RS09960 (DU470_09960)	-	1942609..1943022 (-)	414	WP_025173836.1	hypothetical protein	-
DU470_RS09965 (DU470_09965)	-	1943051..1943161 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=303640 DU470_RS09920 WP_001017131.1 1937537..1938580(-) (vraS) [Staphylococcus aureus strain E16SA093]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=303640 DU470_RS09920 WP_001017131.1 1937537..1938580(-) (vraS) [Staphylococcus aureus strain E16SA093]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1