Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   ETT44_RS05895 Genome accession   NZ_CP035455
Coordinates   1115882..1117981 (+) Length   699 a.a.
NCBI ID   WP_002984939.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm197     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1110882..1122981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT44_RS05870 (ETT44_05870) deoD 1110905..1111618 (-) 714 WP_002984928.1 purine-nucleoside phosphorylase -
  ETT44_RS05875 (ETT44_05875) - 1112281..1113090 (-) 810 WP_002984930.1 purine-nucleoside phosphorylase -
  ETT44_RS05880 (ETT44_05880) arsC 1113074..1113514 (-) 441 WP_002984932.1 arsenate reductase (glutaredoxin) -
  ETT44_RS05885 (ETT44_05885) - 1113533..1114744 (-) 1212 WP_002984934.1 phosphopentomutase -
  ETT44_RS05890 (ETT44_05890) rpiA 1114821..1115504 (-) 684 WP_002984936.1 ribose-5-phosphate isomerase RpiA -
  ETT44_RS05895 (ETT44_05895) clpC 1115882..1117981 (+) 2100 WP_002984939.1 AAA family ATPase Regulator
  ETT44_RS05900 (ETT44_05900) - 1118039..1118782 (-) 744 WP_002984942.1 hypothetical protein -
  ETT44_RS05905 (ETT44_05905) yihA 1118930..1119529 (-) 600 WP_002984945.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ETT44_RS05910 (ETT44_05910) clpX 1119539..1120768 (-) 1230 WP_002984948.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ETT44_RS05915 (ETT44_05915) - 1120898..1121068 (-) 171 WP_002984950.1 hypothetical protein -
  ETT44_RS05920 (ETT44_05920) - 1121088..1121585 (-) 498 WP_002984955.1 dihydrofolate reductase -
  ETT44_RS05925 (ETT44_05925) - 1121665..1122504 (-) 840 WP_010922172.1 thymidylate synthase -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77330.35 Da        Isoelectric Point: 5.5562

>NTDB_id=303577 ETT44_RS05895 WP_002984939.1 1115882..1117981(+) (clpC) [Streptococcus pyogenes strain emm197]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIRQNDQ

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=303577 ETT44_RS05895 WP_002984939.1 1115882..1117981(+) (clpC) [Streptococcus pyogenes strain emm197]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCCGCTATTAAAAACAAAGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACCCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTTGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCTGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTCGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGAGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGAAGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TCAGGCAAAACGATCAGTAA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-600)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(607-678)

AAA lid domain (AAA_lid_9)

(259-353)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

47.084

100

0.474
  clpE Streptococcus mutans UA159

49.224

92.132

0.454
  clpE Streptococcus pneumoniae TIGR4

49.438

89.127

0.441
  clpE Streptococcus pneumoniae Rx1

49.438

89.127

0.441
  clpE Streptococcus pneumoniae D39

49.438

89.127

0.441
  clpE Streptococcus pneumoniae R6

49.438

89.127

0.441
  clpC Bacillus subtilis subsp. subtilis str. 168

44.662

95.136

0.425
  clpC Streptococcus thermophilus LMD-9

42.79

91.273

0.391
  clpC Streptococcus pneumoniae Rx1

41.871

93.276

0.391
  clpC Streptococcus pneumoniae D39

41.871

93.276

0.391
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

41.348

93.419

0.386
  clpC Streptococcus thermophilus LMG 18311

42.587

90.701

0.386
  clpC Streptococcus pneumoniae TIGR4

42.857

90.129

0.386
  clpC Streptococcus mutans UA159

41.719

91.559

0.382

Multiple sequence alignment