Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ETT45_RS05710 Genome accession   NZ_CP035454
Coordinates   1109232..1109894 (-) Length   220 a.a.
NCBI ID   WP_030126965.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm54     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1104232..1114894
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT45_RS09085 - 1104278..1104571 (-) 294 WP_306460904.1 hypothetical protein -
  ETT45_RS05685 (ETT45_05680) - 1104568..1104816 (-) 249 WP_011054656.1 hypothetical protein -
  ETT45_RS05690 (ETT45_05685) - 1104801..1105028 (-) 228 WP_011054657.1 hypothetical protein -
  ETT45_RS05695 (ETT45_05690) sodA 1105195..1105800 (-) 606 WP_002983977.1 superoxide dismutase SodA -
  ETT45_RS05700 (ETT45_05695) holA 1105897..1106937 (-) 1041 WP_030126963.1 DNA polymerase III subunit delta -
  ETT45_RS05705 (ETT45_05700) comEC/celB 1107008..1109251 (-) 2244 WP_030126964.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ETT45_RS05710 (ETT45_05705) comEA/celA/cilE 1109232..1109894 (-) 663 WP_030126965.1 ComEA family DNA-binding protein Machinery gene
  ETT45_RS05715 (ETT45_05710) - 1110094..1110834 (-) 741 WP_011054661.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ETT45_RS05720 (ETT45_05715) - 1110952..1111728 (+) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ETT45_RS05725 (ETT45_05720) - 1111718..1111996 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  ETT45_RS05730 (ETT45_05725) - 1112020..1114020 (-) 2001 WP_030126966.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24607.41 Da        Isoelectric Point: 6.7451

>NTDB_id=303472 ETT45_RS05710 WP_030126965.1 1109232..1109894(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm54]
MLDELLIKGKSFLRERYFPPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=303472 ETT45_RS05710 WP_030126965.1 1109232..1109894(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm54]
ATGTTAGATGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCCGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405