Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   ETT45_RS03840 Genome accession   NZ_CP035454
Coordinates   737465..737941 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain emm54     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 732465..742941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT45_RS03815 (ETT45_03810) - 732506..733294 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  ETT45_RS03820 (ETT45_03815) - 733334..734440 (+) 1107 WP_021733319.1 FAD-binding oxidoreductase -
  ETT45_RS03825 (ETT45_03820) rfbA 734498..735367 (+) 870 WP_010922195.1 glucose-1-phosphate thymidylyltransferase RfbA -
  ETT45_RS03830 (ETT45_03825) - 735367..735960 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  ETT45_RS03835 (ETT45_03830) rfbB 736204..737244 (+) 1041 WP_136129584.1 dTDP-glucose 4,6-dehydratase -
  ETT45_RS03840 (ETT45_03835) mutX 737465..737941 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  ETT45_RS03845 (ETT45_03840) - 737999..739180 (+) 1182 WP_038432925.1 AI-2E family transporter -
  ETT45_RS03850 (ETT45_03845) - 739170..740417 (+) 1248 WP_030126713.1 tetratricopeptide repeat protein -
  ETT45_RS03855 (ETT45_03850) fbp54 740476..742128 (-) 1653 WP_002991968.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=303458 ETT45_RS03840 WP_002984880.1 737465..737941(+) (mutX) [Streptococcus pyogenes strain emm54]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=303458 ETT45_RS03840 WP_002984880.1 737465..737941(+) (mutX) [Streptococcus pyogenes strain emm54]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACTCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703