Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ETT46_RS09615 Genome accession   NZ_CP035453
Coordinates   424935..425153 (+) Length   72 a.a.
NCBI ID   WP_011528334.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm100     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 419935..430153
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT46_RS02340 (ETT46_02340) - 420944..421519 (+) 576 WP_009880369.1 uracil-DNA glycosylase family protein -
  ETT46_RS02345 (ETT46_02345) ybeY 421678..422175 (+) 498 WP_002985748.1 rRNA maturation RNase YbeY -
  ETT46_RS02350 (ETT46_02350) - 422156..422563 (+) 408 WP_002985746.1 diacylglycerol kinase family protein -
  ETT46_RS02355 (ETT46_02355) era 422683..423579 (+) 897 WP_003047080.1 GTPase Era -
  ETT46_RS02360 (ETT46_02360) - 423599..424075 (+) 477 WP_136265123.1 NUDIX hydrolase -
  ETT46_RS09610 (ETT46_02365) - 424380..424634 (-) 255 WP_010921971.1 hypothetical protein -
  ETT46_RS09615 comE/blpR 424935..425153 (+) 219 WP_011528334.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  ETT46_RS09620 - 425350..426956 (-) 1607 Protein_411 ABC transporter transmembrane domain-containing protein -
  ETT46_RS02390 (ETT46_02390) - 427254..427478 (+) 225 WP_002994580.1 Blp family class II bacteriocin -
  ETT46_RS09475 - 427456..427632 (+) 177 WP_002994581.1 hypothetical protein -
  ETT46_RS09785 (ETT46_02395) - 427927..428238 (+) 312 WP_225793061.1 CPBP family intramembrane glutamic endopeptidase -
  ETT46_RS09625 - 428323..428451 (+) 129 WP_002994583.1 hypothetical protein -
  ETT46_RS02400 (ETT46_02400) - 428850..429077 (+) 228 WP_028797129.1 Blp family class II bacteriocin -
  ETT46_RS02405 (ETT46_02405) - 429126..429443 (+) 318 WP_002994587.1 hypothetical protein -

Sequence

Protein


Download         Length: 72 a.a.        Molecular weight: 8680.16 Da        Isoelectric Point: 10.5045

>NTDB_id=303415 ETT46_RS09615 WP_011528334.1 424935..425153(+) (comE/blpR) [Streptococcus pyogenes strain emm100]
MVLYSTRERIEFYGELSEIVKQEPRLFQCHRSFVVNPYNISSIQRLERKIYLKKRFILSSIKAKSYCSKRSS

Nucleotide


Download         Length: 219 bp        

>NTDB_id=303415 ETT46_RS09615 WP_011528334.1 424935..425153(+) (comE/blpR) [Streptococcus pyogenes strain emm100]
TTGGTTCTTTATTCTACTAGAGAAAGGATTGAATTTTATGGGGAGTTATCTGAAATCGTTAAGCAAGAACCAAGATTATT
TCAATGCCATCGATCATTTGTTGTTAATCCCTACAATATATCTTCAATACAACGATTAGAACGTAAGATTTATTTAAAAA
AACGGTTCATCTTGTCTAGTATCAAGGCTAAAAGTTACTGCTCTAAAAGAAGCAGTTGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(3-56)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

56.604

73.611

0.417