Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   ETT46_RS09045 Genome accession   NZ_CP035453
Coordinates   1764649..1765416 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm100     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1759649..1770416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT46_RS09030 (ETT46_09025) hexB 1760158..1762140 (-) 1983 WP_136110754.1 DNA mismatch repair endonuclease MutL Machinery gene
  ETT46_RS09035 (ETT46_09030) - 1762235..1763386 (-) 1152 WP_186789093.1 site-specific integrase -
  ETT46_RS09040 (ETT46_09035) - 1763635..1763778 (+) 144 WP_011185066.1 putative holin-like toxin -
  ETT46_RS09045 (ETT46_09040) irvR 1764649..1765416 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  ETT46_RS09050 (ETT46_09045) - 1765570..1765776 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  ETT46_RS09055 (ETT46_09050) - 1765810..1766577 (+) 768 WP_080277853.1 Bro-N domain-containing protein -
  ETT46_RS09060 (ETT46_09055) - 1766587..1767210 (+) 624 WP_010922760.1 phage repressor protein -
  ETT46_RS09065 (ETT46_09060) - 1767237..1767479 (+) 243 WP_000648623.1 hypothetical protein -
  ETT46_RS09070 (ETT46_09065) - 1767735..1768076 (+) 342 WP_010922762.1 hypothetical protein -
  ETT46_RS09075 (ETT46_09070) - 1768063..1768284 (+) 222 WP_010922763.1 hypothetical protein -
  ETT46_RS09080 (ETT46_09075) - 1768287..1768478 (+) 192 WP_010922764.1 hypothetical protein -
  ETT46_RS09085 (ETT46_09080) - 1768490..1768819 (+) 330 WP_003058810.1 hypothetical protein -
  ETT46_RS09090 (ETT46_09085) - 1768822..1769094 (+) 273 WP_001100459.1 hypothetical protein -
  ETT46_RS09095 (ETT46_09090) - 1769095..1769952 (+) 858 WP_010922767.1 primase alpha helix C-terminal domain-containing protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=303409 ETT46_RS09045 WP_003058809.1 1764649..1765416(-) (irvR) [Streptococcus pyogenes strain emm100]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=303409 ETT46_RS09045 WP_003058809.1 1764649..1765416(-) (irvR) [Streptococcus pyogenes strain emm100]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4