Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ETT46_RS06045 Genome accession   NZ_CP035453
Coordinates   1159659..1160321 (-) Length   220 a.a.
NCBI ID   WP_136110879.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm100     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1154659..1165321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT46_RS06020 (ETT46_06015) - 1154995..1155243 (-) 249 WP_011054656.1 hypothetical protein -
  ETT46_RS06025 (ETT46_06020) - 1155228..1155455 (-) 228 WP_011054657.1 hypothetical protein -
  ETT46_RS06030 (ETT46_06025) sodA 1155622..1156227 (-) 606 WP_002983977.1 superoxide dismutase SodA -
  ETT46_RS06035 (ETT46_06030) holA 1156324..1157364 (-) 1041 WP_136110881.1 DNA polymerase III subunit delta -
  ETT46_RS06040 (ETT46_06035) comEC/celB 1157435..1159678 (-) 2244 WP_136265171.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ETT46_RS06045 (ETT46_06040) comEA/celA/cilE 1159659..1160321 (-) 663 WP_136110879.1 ComEA family DNA-binding protein Machinery gene
  ETT46_RS06050 (ETT46_06045) - 1160521..1161261 (-) 741 WP_011054661.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ETT46_RS06055 (ETT46_06050) - 1161379..1162155 (+) 777 WP_136265173.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ETT46_RS06060 (ETT46_06055) - 1162145..1162423 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  ETT46_RS06065 (ETT46_06060) - 1162447..1164447 (-) 2001 WP_002994363.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24634.43 Da        Isoelectric Point: 6.7451

>NTDB_id=303374 ETT46_RS06045 WP_136110879.1 1159659..1160321(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm100]
MLDELLIKGKSFLRERYFPPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETANKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=303374 ETT46_RS06045 WP_136110879.1 1159659..1160321(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm100]
ATGTTAGATGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCCGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAACAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.512

94.091

0.4