Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   ETT46_RS04190 Genome accession   NZ_CP035453
Coordinates   792602..793078 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain emm100     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 787602..798078
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT46_RS04165 (ETT46_04160) - 787643..788431 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  ETT46_RS04170 (ETT46_04165) - 788471..789577 (+) 1107 WP_020833434.1 FAD-binding oxidoreductase -
  ETT46_RS04175 (ETT46_04170) rfbA 789635..790504 (+) 870 WP_002992970.1 glucose-1-phosphate thymidylyltransferase RfbA -
  ETT46_RS04180 (ETT46_04175) - 790504..791097 (+) 594 WP_136110959.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  ETT46_RS04185 (ETT46_04180) rfbB 791341..792381 (+) 1041 WP_023612000.1 dTDP-glucose 4,6-dehydratase -
  ETT46_RS04190 (ETT46_04185) mutX 792602..793078 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  ETT46_RS04195 (ETT46_04190) - 793136..794317 (+) 1182 WP_038432925.1 AI-2E family transporter -
  ETT46_RS04200 (ETT46_04195) - 794307..795554 (+) 1248 WP_136305247.1 tetratricopeptide repeat protein -
  ETT46_RS04205 (ETT46_04200) fbp54 795614..797266 (-) 1653 WP_136264906.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=303360 ETT46_RS04190 WP_002984880.1 792602..793078(+) (mutX) [Streptococcus pyogenes strain emm100]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=303360 ETT46_RS04190 WP_002984880.1 792602..793078(+) (mutX) [Streptococcus pyogenes strain emm100]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703