Detailed information NTG0303358

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ETT46_RS03960
• Genome accession: NZ_CP035453
• Coordinates: 748638..750737 (-)
• Length: 699 a.a.
• NCBI ID: WP_136264888.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm100
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 743638..755737

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT46_RS03930 (ETT46_03925)	-	744115..744954 (+)	840	WP_010922172.1	thymidylate synthase	-
ETT46_RS03935 (ETT46_03930)	-	745034..745531 (+)	498	WP_002984955.1	dihydrofolate reductase	-
ETT46_RS03940 (ETT46_03935)	-	745551..745721 (+)	171	WP_002984950.1	hypothetical protein	-
ETT46_RS03945 (ETT46_03940)	clpX	745851..747080 (+)	1230	WP_136264886.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT46_RS03950 (ETT46_03945)	yihA	747090..747689 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT46_RS03955 (ETT46_03950)	-	747837..748580 (+)	744	WP_002984942.1	hypothetical protein	-
ETT46_RS03960 (ETT46_03955)	clpC	748638..750737 (-)	2100	WP_136264888.1	AAA family ATPase	Regulator
ETT46_RS03965 (ETT46_03960)	rpiA	751115..751798 (+)	684	WP_136022278.1	ribose-5-phosphate isomerase RpiA	-
ETT46_RS03970 (ETT46_03965)	-	751875..753086 (+)	1212	WP_020905095.1	phosphopentomutase	-
ETT46_RS03975 (ETT46_03970)	arsC	753105..753545 (+)	441	WP_136264890.1	arsenate reductase (glutaredoxin)	-
ETT46_RS03980 (ETT46_03975)	-	753529..754338 (+)	810	WP_136047979.1	purine-nucleoside phosphorylase	-
ETT46_RS03985 (ETT46_03980)	deoD	755003..755716 (+)	714	WP_002990147.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77346.48 Da
• Isoelectric Point: 5.8959

>NTDB_id=303358 ETT46_RS03960 WP_136264888.1 748638..750737(-) (clpC) [Streptococcus pyogenes strain emm100]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGKRPIGSFLFVGPTGVGKTKLAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKESLEEIVDLMLAEVNQTTAKKGISLTITDDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIRQNDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=303358 ETT46_RS03960 WP_136264888.1 748638..750737(-) (clpC) [Streptococcus pyogenes strain emm100]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCCGCTATTAAAAACAAAGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACCCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTTGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTCACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCTGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTCGCAGCAGT
AGCACGTGCTATTCGACGAAATCGGGCAGGTTTTGATGATGGTAAACGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAAAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGAGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAGTTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTACTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGAAGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAACGATCAGTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA lid domain (AAA_lid_9) (259-353)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	46.799	100	0.471
clpE	Streptococcus mutans UA159	48.913	92.132	0.451
clpE	Streptococcus pneumoniae TIGR4	49.117	89.127	0.438
clpE	Streptococcus pneumoniae Rx1	49.117	89.127	0.438
clpE	Streptococcus pneumoniae D39	49.117	89.127	0.438
clpE	Streptococcus pneumoniae R6	49.117	89.127	0.438
clpC	Bacillus subtilis subsp. subtilis str. 168	44.812	95.136	0.426
clpC	Streptococcus thermophilus LMD-9	42.79	91.273	0.391
clpC	Streptococcus pneumoniae Rx1	41.871	93.276	0.391
clpC	Streptococcus pneumoniae D39	41.871	93.276	0.391
clpC	Streptococcus thermophilus LMG 18311	42.633	91.273	0.389
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.348	93.419	0.386
clpC	Streptococcus pneumoniae TIGR4	42.857	90.129	0.386
clpC	Streptococcus mutans UA159	41.719	91.559	0.382