Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ETT47_RS05670 Genome accession   NZ_CP035452
Coordinates   1134207..1134869 (-) Length   220 a.a.
NCBI ID   WP_012560803.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm123     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1129207..1139869
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT47_RS05650 (ETT47_05640) - 1129776..1130003 (-) 228 WP_011054657.1 hypothetical protein -
  ETT47_RS05655 (ETT47_05645) sodA 1130170..1130775 (-) 606 WP_136099207.1 superoxide dismutase SodA -
  ETT47_RS05660 (ETT47_05650) holA 1130872..1131912 (-) 1041 WP_011054659.1 DNA polymerase III subunit delta -
  ETT47_RS05665 (ETT47_05655) comEC/celB 1131983..1134226 (-) 2244 WP_109991704.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ETT47_RS05670 (ETT47_05660) comEA/celA/cilE 1134207..1134869 (-) 663 WP_012560803.1 ComEA family DNA-binding protein Machinery gene
  ETT47_RS05675 (ETT47_05665) - 1135069..1135809 (-) 741 WP_168410086.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ETT47_RS05680 (ETT47_05670) - 1135927..1136703 (+) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ETT47_RS05685 (ETT47_05675) - 1136693..1136971 (+) 279 WP_136099209.1 GIY-YIG nuclease family protein -
  ETT47_RS05690 (ETT47_05680) - 1136995..1138995 (-) 2001 WP_136099210.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24650.47 Da        Isoelectric Point: 6.7451

>NTDB_id=303277 ETT47_RS05670 WP_012560803.1 1134207..1134869(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm123]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETANKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=303277 ETT47_RS05670 WP_012560803.1 1134207..1134869(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm123]
ATGTTAGATGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAACAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.512

94.091

0.4