Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ETT49_RS05385 Genome accession   NZ_CP035450
Coordinates   1063159..1063821 (-) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain emm93.4     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1058159..1068821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT49_RS08875 (ETT49_05360) - 1058722..1058955 (-) 234 WP_002983979.1 hypothetical protein -
  ETT49_RS05370 (ETT49_05365) sodA 1059122..1059727 (-) 606 WP_002983977.1 superoxide dismutase SodA -
  ETT49_RS05375 (ETT49_05370) holA 1059824..1060864 (-) 1041 WP_011054659.1 DNA polymerase III subunit delta -
  ETT49_RS05380 (ETT49_05375) comEC/celB 1060935..1063178 (-) 2244 WP_085634526.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ETT49_RS05385 (ETT49_05380) comEA/celA/cilE 1063159..1063821 (-) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  ETT49_RS05390 (ETT49_05385) - 1064021..1064761 (-) 741 WP_012560804.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ETT49_RS05395 (ETT49_05390) - 1064879..1065655 (+) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ETT49_RS05400 (ETT49_05395) - 1065645..1065923 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  ETT49_RS05405 (ETT49_05400) - 1065947..1067947 (-) 2001 WP_136269399.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=303085 ETT49_RS05385 WP_002995626.1 1063159..1063821(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm93.4]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=303085 ETT49_RS05385 WP_002995626.1 1063159..1063821(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm93.4]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAATTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405