Detailed information NTG0303060

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT49_RS02295
• Genome accession: NZ_CP035450
• Coordinates: 414364..415365 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A0H2UU49
• Organism: Streptococcus pyogenes strain emm93.4
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 409364..420365

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT49_RS02270 (ETT49_02265)	-	410038..410721 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
ETT49_RS02275 (ETT49_02270)	-	410932..411858 (-)	927	WP_110002748.1	glycosyltransferase family 2 protein	-
ETT49_RS02280 (ETT49_02275)	-	412003..412380 (-)	378	WP_002985686.1	VOC family protein	-
ETT49_RS02285 (ETT49_02280)	-	412391..413056 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ETT49_RS02290 (ETT49_02285)	-	413105..414190 (-)	1086	WP_011054264.1	aminopeptidase P family protein	-
ETT49_RS02295 (ETT49_02290)	ccpA	414364..415365 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT49_RS02300 (ETT49_02295)	-	415496..416494 (+)	999	WP_002994184.1	glycosyltransferase family 4 protein	-
ETT49_RS02305 (ETT49_02300)	-	416496..417830 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
ETT49_RS02310 (ETT49_02305)	thrS	418252..420195 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=303060 ETT49_RS02295 WP_002985680.1 414364..415365(+) (ccpA) [Streptococcus pyogenes strain emm93.4]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=303060 ETT49_RS02295 WP_002985680.1 414364..415365(+) (ccpA) [Streptococcus pyogenes strain emm93.4]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterProScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A0H2UU49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559