Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ETT51_RS09290 Genome accession   NZ_CP035448
Coordinates   411248..411466 (+) Length   72 a.a.
NCBI ID   WP_072135532.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm70     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 406248..416466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT51_RS02225 (ETT51_02245) - 407255..407830 (+) 576 WP_009880369.1 uracil-DNA glycosylase family protein -
  ETT51_RS02230 (ETT51_02250) ybeY 407989..408486 (+) 498 WP_032467023.1 rRNA maturation RNase YbeY -
  ETT51_RS02235 (ETT51_02255) - 408467..408874 (+) 408 WP_002985746.1 diacylglycerol kinase family protein -
  ETT51_RS02240 (ETT51_02260) era 408994..409890 (+) 897 WP_063632613.1 GTPase Era -
  ETT51_RS02245 (ETT51_02265) - 409911..410387 (+) 477 WP_038432842.1 NUDIX hydrolase -
  ETT51_RS09285 (ETT51_02270) - 410693..410947 (-) 255 WP_014407373.1 hypothetical protein -
  ETT51_RS09290 comE/blpR 411248..411466 (+) 219 WP_072135532.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  ETT51_RS09295 - 411663..413269 (-) 1607 Protein_392 ABC transporter transmembrane domain-containing protein -
  ETT51_RS02275 (ETT51_02295) - 413567..413791 (+) 225 WP_002994580.1 Blp family class II bacteriocin -
  ETT51_RS09160 - 413769..413945 (+) 177 WP_002994581.1 hypothetical protein -
  ETT51_RS09545 (ETT51_02300) - 414240..414551 (+) 312 WP_225793061.1 CPBP family intramembrane glutamic endopeptidase -
  ETT51_RS09420 - 414636..414764 (+) 129 WP_002994583.1 hypothetical protein -
  ETT51_RS02285 (ETT51_02305) - 415162..415389 (+) 228 WP_028797129.1 Blp family class II bacteriocin -
  ETT51_RS02290 (ETT51_02310) - 415438..415755 (+) 318 WP_002994587.1 hypothetical protein -

Sequence

Protein


Download         Length: 72 a.a.        Molecular weight: 8666.13 Da        Isoelectric Point: 10.5045

>NTDB_id=302932 ETT51_RS09290 WP_072135532.1 411248..411466(+) (comE/blpR) [Streptococcus pyogenes strain emm70]
MVLYSTRERIEFYGELSEIVKQEPRLFQCHRSFVVNPYNISSIQRLERKVYLKKRFILSSIKAKSYCSKRSS

Nucleotide


Download         Length: 219 bp        

>NTDB_id=302932 ETT51_RS09290 WP_072135532.1 411248..411466(+) (comE/blpR) [Streptococcus pyogenes strain emm70]
TTGGTTCTTTATTCTACTAGAGAAAGGATTGAATTTTATGGGGAGTTATCTGAAATCGTTAAGCAAGAACCAAGATTATT
TCAATGCCATCGATCATTTGTTGTTAATCCCTACAATATATCTTCAATACAACGATTAGAACGTAAGGTTTATTTAAAAA
AACGGTTCATCTTGTCTAGTATCAAGGCTAAAAGTTACTGCTCTAAAAGAAGCAGTTGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(3-55)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

56.604

73.611

0.417