Detailed information NTG0302878

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ETT51_RS03835
• Genome accession: NZ_CP035448
• Coordinates: 735005..737104 (-)
• Length: 699 a.a.
• NCBI ID: WP_063632633.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm70
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 730005..742104

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT51_RS03805 (ETT51_03830)	-	730482..731321 (+)	840	WP_011017679.1	thymidylate synthase	-
ETT51_RS03810 (ETT51_03835)	-	731401..731898 (+)	498	WP_002984955.1	dihydrofolate reductase	-
ETT51_RS03815 (ETT51_03840)	-	731918..732088 (+)	171	WP_002990165.1	hypothetical protein	-
ETT51_RS03820 (ETT51_03845)	clpX	732218..733447 (+)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT51_RS03825 (ETT51_03850)	yihA	733457..734056 (+)	600	WP_038432912.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT51_RS03830 (ETT51_03855)	-	734204..734947 (+)	744	WP_002984942.1	hypothetical protein	-
ETT51_RS03835 (ETT51_03860)	clpC	735005..737104 (-)	2100	WP_063632633.1	AAA family ATPase	Regulator
ETT51_RS03840 (ETT51_03865)	rpiA	737482..738165 (+)	684	WP_002994002.1	ribose-5-phosphate isomerase RpiA	-
ETT51_RS03845 (ETT51_03870)	-	738242..739453 (+)	1212	WP_020905095.1	phosphopentomutase	-
ETT51_RS03850 (ETT51_03875)	arsC	739472..739912 (+)	441	WP_038432915.1	arsenate reductase (glutaredoxin)	-
ETT51_RS03855 (ETT51_03880)	-	739896..740705 (+)	810	WP_038432917.1	purine-nucleoside phosphorylase	-
ETT51_RS03860 (ETT51_03885)	deoD	741368..742081 (+)	714	WP_136276045.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77353.37 Da
• Isoelectric Point: 5.6659

>NTDB_id=302878 ETT51_RS03835 WP_063632633.1 735005..737104(-) (clpC) [Streptococcus pyogenes strain emm70]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKERQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLVLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPDVKKLQAILKEGQLVIRQNDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=302878 ETT51_RS03835 WP_063632633.1 735005..737104(-) (clpC) [Streptococcus pyogenes strain emm70]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCACTCGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGGCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCCGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTCGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGAGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAGTGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGACGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAACGATCAGTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

• AAA lid domain (AAA_lid_9) (259-353)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	46.799	100	0.471
clpE	Streptococcus mutans UA159	48.913	92.132	0.451
clpE	Streptococcus pneumoniae TIGR4	49.278	89.127	0.439
clpE	Streptococcus pneumoniae Rx1	49.278	89.127	0.439
clpE	Streptococcus pneumoniae D39	49.278	89.127	0.439
clpE	Streptococcus pneumoniae R6	49.278	89.127	0.439
clpC	Bacillus subtilis subsp. subtilis str. 168	44.511	95.136	0.423
clpC	Streptococcus thermophilus LMD-9	42.79	91.273	0.391
clpC	Streptococcus pneumoniae Rx1	41.718	93.276	0.389
clpC	Streptococcus pneumoniae D39	41.718	93.276	0.389
clpC	Streptococcus thermophilus LMG 18311	42.633	91.273	0.389
clpC	Streptococcus pneumoniae TIGR4	42.698	90.129	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.194	93.419	0.385
clpC	Streptococcus mutans UA159	41.562	91.559	0.381