Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   ETT51_RS00670 Genome accession   NZ_CP035448
Coordinates   104534..104962 (+) Length   142 a.a.
NCBI ID   WP_023605232.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm70     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99534..109962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT51_RS00650 (ETT51_00655) - 101865..102230 (+) 366 WP_002986560.1 DUF1033 family protein -
  ETT51_RS00655 (ETT51_00660) comGA 102323..103261 (+) 939 WP_063632550.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT51_RS00660 (ETT51_00665) comGB 103197..104231 (+) 1035 WP_225793059.1 competence type IV pilus assembly protein ComGB Machinery gene
  ETT51_RS00665 (ETT51_00670) comGC 104233..104559 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT51_RS00670 (ETT51_00675) comGD 104534..104962 (+) 429 WP_023605232.1 competence type IV pilus minor pilin ComGD Machinery gene
  ETT51_RS00675 (ETT51_00680) comGE 104919..105203 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  ETT51_RS00680 (ETT51_00685) comGF 105196..105630 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT51_RS00685 (ETT51_00690) comGG 105614..105940 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  ETT51_RS00690 (ETT51_00695) comGH 106038..106991 (+) 954 WP_023610092.1 class I SAM-dependent methyltransferase Machinery gene
  ETT51_RS00695 (ETT51_00700) - 107050..108246 (+) 1197 WP_002992742.1 acetate kinase -
  ETT51_RS00700 (ETT51_00705) - 108433..108741 (+) 309 WP_032467031.1 hypothetical protein -
  ETT51_RS00705 (ETT51_00710) proC 108824..109594 (-) 771 WP_002992745.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16256.99 Da        Isoelectric Point: 10.1022

>NTDB_id=302845 ETT51_RS00670 WP_023605232.1 104534..104962(+) (comGD) [Streptococcus pyogenes strain emm70]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRCFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=302845 ETT51_RS00670 WP_023605232.1 104534..104962(+) (comGD) [Streptococcus pyogenes strain emm70]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGATGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA140

44.961

90.845

0.408
  comGD Streptococcus mutans UA159

44.961

90.845

0.408
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366

Multiple sequence alignment