Detailed information NTG0302780

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ETT52_RS03550
• Genome accession: NZ_CP035447
• Coordinates: 685758..687857 (-)
• Length: 699 a.a.
• NCBI ID: WP_136026178.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm97.1
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 680758..692857

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT52_RS03520 (ETT52_03510)	-	681235..682074 (+)	840	WP_011017679.1	thymidylate synthase	-
ETT52_RS03525 (ETT52_03515)	-	682154..682651 (+)	498	WP_002984955.1	dihydrofolate reductase	-
ETT52_RS09265 (ETT52_03520)	-	682671..682841 (+)	171	WP_002990165.1	hypothetical protein	-
ETT52_RS03535 (ETT52_03525)	clpX	682971..684200 (+)	1230	WP_002984948.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT52_RS03540 (ETT52_03530)	yihA	684210..684809 (+)	600	WP_011184414.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT52_RS03545 (ETT52_03535)	-	684957..685700 (+)	744	WP_002984942.1	hypothetical protein	-
ETT52_RS03550 (ETT52_03540)	clpC	685758..687857 (-)	2100	WP_136026178.1	AAA family ATPase	Regulator
ETT52_RS03555 (ETT52_03545)	rpiA	688235..688918 (+)	684	WP_009881270.1	ribose-5-phosphate isomerase RpiA	-
ETT52_RS03560 (ETT52_03550)	-	688995..690206 (+)	1212	WP_020905095.1	phosphopentomutase	-
ETT52_RS03565 (ETT52_03555)	arsC	690225..690665 (+)	441	WP_063812328.1	arsenate reductase (glutaredoxin)	-
ETT52_RS03570 (ETT52_03560)	-	690649..691458 (+)	810	WP_010922178.1	purine-nucleoside phosphorylase	-
ETT52_RS03575 (ETT52_03565)	deoD	692121..692834 (+)	714	WP_002984928.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77360.51 Da
• Isoelectric Point: 5.9831

>NTDB_id=302780 ETT52_RS03550 WP_136026178.1 685758..687857(-) (clpC) [Streptococcus pyogenes strain emm97.1]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEHHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKERQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSGPNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIRQKDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=302780 ETT52_RS03550 WP_136026178.1 685758..687857(-) (clpC) [Streptococcus pyogenes strain emm97.1]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGACATCTTGACCCCGTCATTGGTCGTAACAAAGAAATCCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAATATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCACTCGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACACCACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGGCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCCGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTTGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGGGCCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGACTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGAAGTCAAAAAACTTCAGGCAATTCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAAAGATCAGTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA lid domain (AAA_lid_9) (259-353)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.084	100	0.474
clpE	Streptococcus mutans UA159	49.531	91.559	0.454
clpE	Streptococcus pneumoniae Rx1	49.438	89.127	0.441
clpE	Streptococcus pneumoniae R6	49.438	89.127	0.441
clpE	Streptococcus pneumoniae D39	49.438	89.127	0.441
clpE	Streptococcus pneumoniae TIGR4	49.438	89.127	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	44.662	95.136	0.425
clpC	Streptococcus thermophilus LMD-9	42.947	91.273	0.392
clpC	Streptococcus thermophilus LMG 18311	42.79	91.273	0.391
clpC	Streptococcus pneumoniae D39	41.871	93.276	0.391
clpC	Streptococcus pneumoniae Rx1	41.871	93.276	0.391
clpC	Streptococcus pneumoniae TIGR4	42.857	90.129	0.386
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.194	93.419	0.385
clpC	Streptococcus mutans UA159	41.406	91.559	0.379